Kułak Wojciech, Sobaniec Wojciech, Sołowiej Elzbieta, Boćkowski Leszek
Department of Pediatric Neurology and Rehabilitation, Medical University of Białystok, Poland.
Pediatr Rehabil. 2006 Jul-Sep;9(3):201-9. doi: 10.1080/13638490500343179.
To determine if there is any association between the findings of visual evoked potentials (VEPs), somatosensory evoked potentials (SEPs), and magnetic resonance imaging (MRI) findings with the neurodevelopment and severity in children with cerebral palsy (CP).
The present study included 15 children with spastic diplegic CP and five children with spastic hemiplegic CP and 42 healthy children as controls. The number of the controls was two-times greater than the study group to increase statistical power of this study. VEPs and SEPs were recorded in the CP children and compared with healthy controls. All MR scans were obtained using a 1.5 T MR scanner.
A significant difference was found in the latencies P100 (VEP) between the CP and controls. No correlations between increased P100 latencies and asphyxia, prematurity, the CP severity, MRI findings and mental retardation were noted. A significant difference in N13-N20 conductions (SEPs) between the subjects with CP and the control group was found. SEPs were positively correlated with mental retardation in CP children. The brain lesions in MRI showed a significant correlation with the CP severity scores and mental retardation.
The differences in VEPs and SEPs were determined between CP children and healthy children. The MRI findings were positively correlated with the CP severity and mental retardation.
确定脑性瘫痪（CP）患儿的视觉诱发电位（VEP）、体感诱发电位（SEP）结果及磁共振成像（MRI）结果与神经发育和严重程度之间是否存在关联。
本研究纳入15例痉挛型双瘫CP患儿、5例痉挛型偏瘫CP患儿以及42例健康儿童作为对照。为提高本研究的统计学效力，对照组人数是研究组的两倍。对CP患儿记录VEP和SEP，并与健康对照进行比较。所有MR扫描均使用1.5T MR扫描仪获得。
CP患儿与对照组之间在P100（VEP）潜伏期方面存在显著差异。未发现P100潜伏期延长与窒息、早产、CP严重程度、MRI结果及智力发育迟缓之间存在相关性。发现CP患儿与对照组在N13-N20传导（SEP）方面存在显著差异。CP患儿的SEP与智力发育迟缓呈正相关。MRI中的脑损伤与CP严重程度评分及智力发育迟缓呈显著相关。
确定了CP患儿与健康儿童在VEP和SEP方面的差异。MRI结果与CP严重程度及智力发育迟缓呈正相关。
