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脑瘫患儿大脑可塑性的神经生理学研究

Neurophysiologic studies of brain plasticity in children with cerebral palsy.

作者信息

Kułak W, Sobaniec W, Boćkowski L, Sołowiej E, Smigielska-Kuzia J, Artemowicz B, Sendrowski K

机构信息

Department of Pediatric Neurology and Rehabilitation, Medical University of Białystok, Poland.

出版信息

Rocz Akad Med Bialymst. 2005;50 Suppl 1:74-7.

Abstract

The mechanisms of brain plasticity include: a change in the balance of excitation and inhibition; a long-term potentiation or long-term depression; a change in neuronal membrane excitability; the anatomical changes-formation of new axon terminals and new synapses. There are few tools for brain plasticity investigations. The utility of the neurophysiologic in the determination of brain reorganization and repair in patients with cerebral palsy (CP) are described. The authors discuss also their results of quantitative EEG, visual evoked potentials (VEPs) and somatosensory evoked potentials (SEPs) in children with CP. They showed the existence of brain reorganization and repair in children with CP.

摘要

大脑可塑性的机制包括

兴奋与抑制平衡的改变;长时程增强或长时程抑制;神经元膜兴奋性的改变;解剖学变化——新轴突终末和新突触的形成。用于大脑可塑性研究的工具很少。本文描述了神经生理学在确定脑瘫(CP)患者大脑重组和修复方面的效用。作者还讨论了他们对CP患儿进行定量脑电图、视觉诱发电位(VEP)和体感诱发电位(SEP)的研究结果。他们表明CP患儿存在大脑重组和修复现象。

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