Reinhart K, Brunkhorst F, Bone H, Gerlach H, Gründling M, Kreymann G, Kujath P, Marggraf G, Mayer K, Meier-Hellmann A, Peckelsen C, Putensen C, Quintel M, Ragaller M, Rossaint R, Stüber F, Weiler N, Welte T, Werdan K
Deutsche Sepsis-Gesellschaft e V c/o Universitatsklinikum Jena, Erlanger Allee 101, 07747 Jena.
Anaesthesist. 2006 Jun;55 Suppl 1:43-56.
A recent survey conducted by the publicly funded Competence Network Sepsis (SepNet) reveals that severe sepsis and/or septic shock occurs in 75,000 inhabitants (110 out of 100,000) and sepsis in 79,000 inhabitants (116 out of 100,000) in Germany annually. This illness is responsible for approximately 60,000 deaths and ranges as the third most frequent cause of death after acute myocardial infarction. Direct costs for the intensive care of patients with severe sepsis alone amount to approximately 1.77 billion euros, which means that about 30% of the budget in intensive care is used to treat severe sepsis. However, until now German guidelines for the diagnosis and therapy of severe sepsis did not exist. Therefore, the German Sepsis Society initiated the development of guidelines which are based on international recommendations by the International Sepsis Forum (ISF) and the Surviving Sepsis Campaign (SSC) and take into account the structure and organization of the German health care system. Priority was given to the following guideline topics: a) diagnosis, b) prevention, c) causative therapy, d) supportive therapy, e) adjunctive therapy. The guidelines development process was carefully planned and strictly adhered to the requirements of the Working Group of Scientific Medical Societies (AWMF).
由公共资助的脓毒症能力网络（SepNet）近期开展的一项调查显示，在德国，每年有7.5万居民（每10万人中有110人）发生严重脓毒症和/或脓毒性休克，7.9万居民（每10万人中有116人）发生脓毒症。这种疾病导致约6万人死亡，是仅次于急性心肌梗死的第三大常见死因。仅严重脓毒症患者的重症监护直接费用就约达17.7亿欧元，这意味着重症监护预算中约30%用于治疗严重脓毒症。然而，到目前为止，德国尚无严重脓毒症的诊断和治疗指南。因此，德国脓毒症协会启动了指南的制定工作，该指南以国际脓毒症论坛（ISF）和拯救脓毒症运动（SSC）的国际建议为基础，并考虑了德国医疗保健系统的结构和组织。以下指南主题被列为优先事项：a）诊断，b）预防，c）病因治疗，d）支持治疗，e）辅助治疗。指南制定过程经过精心规划，并严格遵守科学医学协会工作组（AWMF）的要求。
