一名免疫功能正常的孕妇发生播散性鸟分枝杆菌复合群感染。
Disseminated Mycobacterium avium complex infection in an immunocompetent pregnant woman.
作者信息
Song Joon Young, Park Cheong Won, Kee Sae Yoon, Choi Won Seok, Kang Eun Young, Sohn Jang Wook, Kim Woo Joo, Kim Min Ja, Cheong Hee Jin
机构信息
Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
出版信息
BMC Infect Dis. 2006 Oct 22;6:154. doi: 10.1186/1471-2334-6-154.
BACKGROUND
Disseminated mycobacterium avium complex (MAC) occurs mainly in immunocompromised hosts, which is associated with abnormal cellular immunity.
CASE PRESENTATION
A 26-year-old pregnant woman presented with fever and general weakness. Miliary lung nodules were noted on chest X-ray. Under the impression of miliary tuberculosis, anti-tuberculosis medication was administered. However, the patient was not improved. Further work-up demonstrated MAC in the sputum and placenta. The patient was treated successfully with clarithromycin-based combination regimen.
CONCLUSION
This appears to be the first case of disseminated MAC in an otherwise healthy pregnant woman. Clinicians should be alert for the diagnosis of MAC infection in diverse clinical conditions.
背景
播散性鸟分枝杆菌复合体（MAC）主要发生于免疫功能低下的宿主，这与细胞免疫异常有关。
病例报告
一名26岁孕妇出现发热和全身乏力。胸部X线检查发现粟粒状肺结节。根据粟粒性肺结核的诊断印象，给予抗结核药物治疗。然而，患者病情并未改善。进一步检查发现痰液和胎盘中存在MAC。患者接受基于克拉霉素的联合治疗方案后成功治愈。
结论
这似乎是首例在其他方面健康的孕妇中发生播散性MAC的病例。临床医生在各种临床情况下应警惕MAC感染的诊断。
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