Kimura M, Kato M, Shimazaki H
Department of Physiology, Jichi Medical School, Tochigi-ken, Japan.
Exp Brain Res. 1990;82(3):672-6. doi: 10.1007/BF00228811.
In order to study neuronal information transfer from the striatum to the globus pallidus (GP) during voluntary movement, we recorded activity of electrophysiologically identified projection neurons in the putamen to the GP while the monkey was performing learned movement tasks. Two categories of putamen neurons were recorded: one with tonic spontaneous discharges at about 2-7 impulses/s responded to external sensory stimuli (type I); the other with very low spontaneous discharge rates less than 0.5 impulses/s showed phasic burst discharges which were time-locked to limb or orofacial movements (type II). All of the putamen neurons identified as projecting to the GP (external and/or internal segment) by an antidromic activation from electrical stimulation of the GP were type II cells. It was concluded that the movement-related activity of type II putamen neurons is transferred to GP and/or SN during voluntary movement but tonically active type I cells do not project to the GP.
为了研究在自主运动过程中从纹状体到苍白球（GP）的神经元信息传递，我们在猴子执行习得的运动任务时，记录了电生理鉴定的从壳核到苍白球的投射神经元的活动。记录了两类壳核神经元：一类是约2-7次冲动/秒的紧张性自发放电，对外部感觉刺激有反应（I型）；另一类是自发放电率极低，小于0.5次冲动/秒，表现为与肢体或口面部运动锁时的相位爆发性放电（II型）。通过对苍白球电刺激的逆向激活鉴定为投射到苍白球（外部和/或内部节段）的所有壳核神经元均为II型细胞。得出的结论是，在自主运动过程中，II型壳核神经元的运动相关活动传递到了苍白球和/或黑质，但紧张性活动的I型细胞不投射到苍白球。
