Cleator Iain G M, Birmingham Carl Laird, Kovacevic Senka, Cleator Maria M, Gritzner Susan
Department of Surgery, University of British Columbia, Vancouver, BC, Canada.
Obes Surg. 2006 Oct;16(10):1337-41. doi: 10.1381/096089206778663850.
The long-term effects of ileogastrostomy surgery for morbid obesity on diabetes mellitus and sleep apnea were investigated.
All patients who had the ileogastrostomy for morbid obesity at the Bariatric Surgery Clinic of St. Paul's Hospital between 1997 and 2002 were registered in the International Bariatric Surgery Registry (IBSR). In 2005, IBSR follow-up was supplemented with a survey.
Of the 592 consecutive patients registered in the IBSR, 311 were available for follow-up. Of the 15 patients who had diabetes mellitus preoperatively, 12 (80%) had cure of their diabetes mellitus and 3 (20%) were improved. Remission or improvement of diabetes occurred early postoperatively. Of the 20 who had sleep apnea preoperatively, 11 (55%) were cured and 6 (30%) were improved.
This is the first report of the long-term effect of the ileogastrostomy on diabetes mellitus and sleep apnea. The ileogastrostomy was associated with rapid improvement or normalization of diabetes mellitus, similar to the biliopancreatic diversion and the Roux-en-Y gastric bypass, but faster than other bariatric operations. Improvement in sleep apnea was slower and was related to weight loss, similar to other bariatric operations.
研究了回肠胃造口术治疗病态肥胖对糖尿病和睡眠呼吸暂停的长期影响。
1997年至2002年期间在圣保罗医院减肥手术诊所接受回肠胃造口术治疗病态肥胖的所有患者均被登记在国际减肥手术登记处（IBSR）。2005年，通过一项调查对IBSR随访进行了补充。
在IBSR登记的592例连续患者中，有311例可供随访。术前患有糖尿病的15例患者中，12例（80%）糖尿病得到治愈，3例（20%）病情改善。糖尿病的缓解或改善在术后早期出现。术前患有睡眠呼吸暂停的20例患者中，11例（55%）治愈，6例（30%）病情改善。
这是关于回肠胃造口术对糖尿病和睡眠呼吸暂停长期影响的首次报告。回肠胃造口术与糖尿病的快速改善或正常化相关，类似于胆胰分流术和Roux-en-Y胃旁路术，但比其他减肥手术更快。睡眠呼吸暂停的改善较慢，且与体重减轻有关，类似于其他减肥手术。
