Klinge Lone Gabriels, Kjeldsen Jens
Odense Universitetshospital, Medicinsk Gastroenterologisk Afdeling S, Odense C.
Ugeskr Laeger. 2006 Oct 9;168(41):3516-8.
Pouchitis is an idiopathic inflammatory bowel disease, which occurs in up to 50% of patients operated on for ulcerative colitis with ileal pouch-anal anastomosis (IPAA). Treatment of pouchitis is still to a large extent empirical, but recently more randomized, double-blind placebo-controlled trials have been conducted. This article reviews the possible treatments for pouchitis, focusing especially on treatment with probiotics, which seem to be a new and promising alternative to antibiotics. We are currently doing clinical trials to determine whether a probiotic is an effective treatment for chronic inflammatory bowel disease.
储袋炎是一种特发性炎症性肠病，在接受回肠储袋肛管吻合术（IPAA）治疗溃疡性结肠炎的患者中，发病率高达50%。储袋炎的治疗在很大程度上仍基于经验，但最近已经开展了更多随机、双盲、安慰剂对照试验。本文综述了储袋炎可能的治疗方法，尤其着重于益生菌治疗，这似乎是一种替代抗生素的新的、有前景的方法。我们目前正在进行临床试验，以确定益生菌是否是治疗慢性炎症性肠病的有效方法。
