Böhm S, Kruis W
Evangelisches Krankenhaus Kalk, Köln.
MMW Fortschr Med. 2006 Aug 31;148(35-36):30-4.
Current data show that probiotics are more effective in preventing the recrudescence of an inflammatory process than in suppressing active disease. This is reflected in the solid evidence for the effect of E. coli Nissle 1917 (Mutaflor) in the maintenance of remission of ulcerative colitis, and of VSL#3 in preventing the recurrence of pouchitis. These indications have since been incorporated in valid guidelines. Initial clinical studies have also provided promising results regarding the efficacy of VSL#3 in preventing pouchitis immediately following proctocolectomy.
目前的数据表明，益生菌在预防炎症过程复发方面比抑制活动性疾病更有效。这体现在大肠杆菌Nissle 1917（慕特福）对维持溃疡性结肠炎缓解的作用以及VSL#3对预防袋炎复发的作用的确凿证据中。这些适应症此后已被纳入有效的指南。初步临床研究也提供了关于VSL#3在直肠结肠切除术后立即预防袋炎疗效的有希望的结果。
