Lundin A, de Boussard C, Edman G, Borg J
Department of Psychiatry, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.
Brain Inj. 2006 Jul;20(8):799-806. doi: 10.1080/02699050600744327.
Examine frequency, character and course of symptoms until 3 months after MTBI and the relation between symptoms and disability.
Prospective cohort study of 122 consecutive patients with MTBI. Symptom assessment after 1, 7 and 14 days and 3 months post-injury by use of Rivermead Post-concussional Questionnaire. Disability assessment by use of Rivermead Head Injury Follow-up Questionnaire.
Patients reporting one or more symptoms declined from 86% on day 1 to 49% 3 months post-injury, when 25% also reported change in one or more domains of everyday activities. Poor memory, sleep disturbance and fatigue were most commonly reported. Symptom and disability scores were correlated (tau = 0.60; p < 0.001). Early symptom load correlated with late symptom load (tau = 0.38; p < 0.01).
Symptoms gradually decline post-injury. Symptoms correlate with disability at 3 months. Patients with early high symptom load are at risk for developing persisting complaints.
研究轻度创伤性脑损伤（MTBI）后3个月内症状的发生频率、特征及病程，以及症状与残疾之间的关系。
对122例连续的MTBI患者进行前瞻性队列研究。在受伤后1天、7天、14天及3个月时，使用Rivermead脑震荡后问卷进行症状评估。使用Rivermead头部损伤随访问卷进行残疾评估。
报告有一个或多个症状的患者比例从受伤第1天的86%下降至受伤后3个月的49%，此时有25%的患者还报告了日常活动一个或多个领域的变化。记忆力差、睡眠障碍和疲劳是最常报告的症状。症状评分与残疾评分相关（tau = 0.60；p < 0.001）。早期症状负荷与晚期症状负荷相关（tau = 0.38；p < 0.01）。
受伤后症状逐渐减轻。3个月时症状与残疾相关。早期症状负荷高的患者有出现持续不适的风险。
