Hekman P R, Bos A J, Cunha R S, Moriguchi Y
Geriatrics Institute of the Pontifical, Catholic University of the Rio Grande do Sul, Porto Alegre, Brazil.
J Cardiovasc Pharmacol. 1990;16 Suppl 8:S12-4.
The Cardiovascular Diseases and Alimentary Comparison (CARDIAC) Study (1) was designed to study the relationship of dietary factors to blood pressure (BP) and other major cardiovascular disease (CVD) in widely different populations of both industralized and developing countries. The primary aim of the research was to test specific hypotheses linking the intake of certain dietary constituents, e.g., sodium (Na), potassium (K), calcium (Ca), and protein, to BP (core study). The final aim was to contribute to the scientific information base required to guide the formulation of dietary goals for the primary prevention of CVD. The results of the preliminary analysis of data from Brazil in 57 inhabitants (22 men and 35 women) suggest a nonsignificant statistical correlation of Na intake estimated by urinary Na excretion and diastolic BP (DBP) and systolic BP (SBP) (p greater than 0.05), K intake estimated by urinary K excretion for DBP and SBP (p greater than 0.05), and taurine intake estimated by taurine urinary excretion for DBP and SBP (p greater than 0.05). A positive correlation was found between body mass index (BMI) and BP (p less than 0.01), for both DBP and SBP.
心血管疾病与饮食比较（CARDIAC）研究（1）旨在研究工业化国家和发展中国家广泛不同人群中饮食因素与血压（BP）及其他主要心血管疾病（CVD）之间的关系。该研究的主要目的是检验将某些饮食成分（如钠（Na）、钾（K）、钙（Ca）和蛋白质）的摄入量与血压联系起来的特定假设（核心研究）。最终目的是为指导制定CVD一级预防饮食目标所需的科学信息库做出贡献。对巴西57名居民（22名男性和35名女性）数据的初步分析结果表明，通过尿钠排泄估算的钠摄入量与舒张压（DBP）和收缩压（SBP）之间无显著统计学相关性（p大于0.05），通过尿钾排泄估算的钾摄入量与DBP和SBP之间无显著相关性（p大于0.05），通过尿牛磺酸排泄估算的牛磺酸摄入量与DBP和SBP之间无显著相关性（p大于0.05）。体重指数（BMI）与DBP和SBP的血压之间均呈正相关（p小于0.01）。
