Karsenti Eric, Nédélec François, Surrey Thomas
European Molecular Systems Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
Nat Cell Biol. 2006 Nov;8(11):1204-11. doi: 10.1038/ncb1498.
The cellular cytoskeleton is well studied in terms of its biological and physical properties, making it an attractive subject for systems approaches. Here, we describe the experimental and theoretical strategies used to study the collective behaviour of microtubules and motors. We illustrate how this led to the beginning of an understanding of dynamic cellular patterns that have precise functions.
细胞细胞骨架在其生物学和物理特性方面得到了充分研究,这使其成为系统方法研究的一个有吸引力的对象。在这里,我们描述了用于研究微管和马达集体行为的实验和理论策略。我们说明了这是如何促成对具有精确功能的动态细胞模式的初步理解的。