Luque I, Fernández-Garayzábal J F, Blume V, Maldonado A, Astorga R, Tarradas C
Departamento de Sanidad Animal, Facultad de Veterinaria, Campus Universitario de Rabanales, 14071 Córdoba, Spain.
J Vet Med B Infect Dis Vet Public Health. 2006 Nov;53(9):451-4. doi: 10.1111/j.1439-0450.2006.01001.x.
The anti-microbial susceptibility and genetic diversity of 65 strains of Streptococcus equi ssp. zooepidemicus (Sez) isolated from mares presenting clinical signs of endometritis was determined by disk agar diffusion and pulsed field gel electrophoresis (PFGE) methods, respectively. Overall, Sez isolates were susceptible to beta-lactams, enrofloxacin, trimethoprim-sulfamethoxazole and gentamicin. These anti-microbials could be recommended as empiric anti-microbial therapy in cases of endometritis caused by Sez. Pulsed field gel electrophoresis typing revealed a great genetic diversity (56 different PFGE macrorestriction profiles) and a low level of genetic relatedness amongst the isolates.
采用纸片琼脂扩散法和脉冲场凝胶电泳（PFGE）方法，分别测定了从表现出子宫内膜炎临床症状的母马中分离出的65株马链球菌兽疫亚种（Sez）的抗菌药敏性和遗传多样性。总体而言，Sez分离株对β-内酰胺类、恩诺沙星、甲氧苄啶-磺胺甲恶唑和庆大霉素敏感。这些抗菌药物可推荐用于Sez引起的子宫内膜炎病例的经验性抗菌治疗。脉冲场凝胶电泳分型显示出巨大的遗传多样性（56种不同的PFGE宏观限制性图谱），且分离株之间的遗传相关性较低。
