Fields David A, Kearney Jay T, Copeland Kenneth C
University of Oklahoma Health Sciences Center, School of Medicine, Department of Pediatrics, Oklahoma University Children's Physicians Diabetes and Endocrinology, 940 NE Thirteenth Street, CH 2B2426, Oklahoma City, OK 73104, USA.
Obesity (Silver Spring). 2006 Oct;14(10):1755-61. doi: 10.1038/oby.2006.202.
To assess the validity of a new hand-held indirect calorimeter [MedGem (MG)] in the determination of resting energy expenditure (REE; kilocalories per day) in children.
One hundred male (n = 54) and female (n = 46) children (10.6 +/- 3.2 years, 43.9 +/- 19.0 kg, 146.1 +/- 18.8 cm, 19.6 +/- 4.9 kg/m(2)) participated. Children arrived at the University of Oklahoma body composition laboratory between 5:30 am and 6:15 am after an overnight fast. On arrival, subjects voided and remained quietly in the supine position for 15 minutes before testing. REE was measured by indirect calorimetry (in random order), with both the MG (sitting upright) and the criterion Delta Trac II (DT) (supine). Data are reported as the mean +/- standard deviation.
The mean MG REE (1452 +/- 355 kcal/d) was significantly higher than DT REE (1349 +/- 296 kcal/d, p < 0.001). Bland-Altman analysis revealed a mean bias (MG - DT) of 104 kcal/d, with limits of agreement of -241 to +449 kcal/d. To examine the difference in subject positioning, an independent sample of 38 subjects performed the MG in its normal position (sitting) and holding the MG in a supine position. REE by the MG in the sitting position (1475 +/- 350 kcal/d) was significantly (p < 0.05) higher than the MG in the supine position (1419 +/- 286 kcal/d).
The mean difference in REE between MG and DT was relatively small (103 kcal/d) but significant; however, a portion of this difference may have been related to differences in subject positioning. These preliminary data indicate that the MG shows promise as a valid tool in the assessment of REE in children.
评估一种新型手持式间接热量测定仪[MedGem（MG）]在测定儿童静息能量消耗（REE；千卡/天）方面的有效性。
100名儿童参与研究，其中男性54名，女性46名（年龄10.6±3.2岁，体重43.9±19.0千克，身高146.1±18.8厘米，体重指数19.6±4.9千克/平方米）。儿童在隔夜禁食后，于上午5:30至6:15抵达俄克拉荷马大学身体成分实验室。到达后，受试者排尿，然后在测试前安静仰卧15分钟。通过间接热量测定法（随机顺序）测量REE，同时使用MG（直立坐姿）和标准的Delta Trac II（DT）（仰卧位）。数据以平均值±标准差表示。
MG测得的平均REE（1452±355千卡/天）显著高于DT测得的REE（1349±296千卡/天，p<0.001）。Bland-Altman分析显示平均偏差（MG - DT）为104千卡/天，一致性界限为-241至+449千卡/天。为研究受试者体位差异的影响，选取38名受试者组成独立样本，分别在MG正常位置（坐姿）和仰卧位手持MG进行测量。MG在坐姿时测得的REE（1475±350千卡/天）显著高于仰卧位时（1419±286千卡/天，p<0.05）。
MG与DT测得的REE平均差异相对较小（103千卡/天）但具有统计学意义；然而，部分差异可能与受试者体位不同有关。这些初步数据表明，MG有望成为评估儿童REE的有效工具。
