Grabarczyk M, Kopeć-Szlezak J, Szczepańska I, Woźniak J, Podstawka U
Institute of Hematology, Department of Physiopathology, Warsaw, Chocimska, Poland.
Haematologia (Budap). 1990;23(3):171-9.
The effect of intragastric administration of gamma-hexachlorocyclohexane (lindane) on peripheral blood cells, kidney and liver was studied in rabbits. White blood cells were found to be most affected by lindane, as was shown by the reduced phagocytic activity of neutrophils and the increased number of lymphocytes with inactive nucleoli. The changes in the characteristics of erythrocyte cell membranes depended on the length of time lindane was administered and on its withdrawal. Histological examination of the liver and kidney showed focal degeneration of tissue and cell structure.
研究了兔经胃内给予γ-六氯环己烷（林丹）对其外周血细胞、肾脏和肝脏的影响。发现白细胞受林丹影响最大，表现为中性粒细胞吞噬活性降低以及核仁不活跃的淋巴细胞数量增加。红细胞细胞膜特性的变化取决于林丹给药时间的长短及其停药情况。肝脏和肾脏的组织学检查显示组织和细胞结构的局灶性变性。
