Guven Esref O, Kilciler Mete, Bedir Selahattin, Avci Ali, Ozgok Yasar
Urology Department, Mustafa Kemal University-Hatay, Hatay, Turkey.
Int Urol Nephrol. 2007;39(3):829-31. doi: 10.1007/s11255-006-9111-8. Epub 2006 Oct 25.
Transitional cell carcinoma (TCC) of the bladder is the seventh most frequent cancer of women. The possible mechanisms of local tumor recurrence are seeding and multicentricity. Distant metastases are most frequently as a result of vascular or lymphatic spread and to a lesser extent by seeding of the tumor cells with urine or transurethral instrumentation. We report a clitoral metastasis of a TCC of the bladder, which is a very unexpected and extremely rare site for metatstasis and discuss whether the possible mechanism is vascular spreading or direct seeding. To our knowledge this is the third case in the literature.
膀胱移行细胞癌(TCC)是女性中第七常见的癌症。局部肿瘤复发的可能机制是种植和多中心性。远处转移最常见的原因是血管或淋巴扩散,较少程度是由于肿瘤细胞随尿液或经尿道器械种植。我们报告了一例膀胱TCC的阴蒂转移,这是一个非常意外且极其罕见的转移部位,并讨论了可能的机制是血管扩散还是直接种植。据我们所知,这是文献中的第三例。