Lerner L B, Andrews S J, Gonzalez J L, Heaney J A, Currie J L
Department of Urology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.
J Reprod Med. 1999 Aug;44(8):729-32.
Gynecologists are frequently asked to evaluate patients with vulvar lesions. Although the differential diagnosis of a vulvar lesion is varied, the main concern is to rule out a vulvar malignancy. Primary vulvar carcinoma is uncommon, and a metastatic cancer from an extragenital site involving the vulva is even more rare.
A 78-year-old woman with a history of a transitional cell carcinoma (TCC) of the bladder presented with two painful vulvar lesions, which represented the first manifestation of metastatic disease. This is the fifth reported case of TCC from the bladder with metastases to the vulva.
The differential diagnosis of a vulvar lesion, especially in a woman with a prior history of renal tract malignancy, should include metastatic lesions.
妇科医生经常被要求评估患有外阴病变的患者。尽管外阴病变的鉴别诊断多种多样,但主要关注点是排除外阴恶性肿瘤。原发性外阴癌并不常见,而来自生殖器外部位累及外阴的转移性癌则更为罕见。
一名78岁有膀胱移行细胞癌(TCC)病史的女性出现两个疼痛性外阴病变,这是转移性疾病的首次表现。这是第五例报道的膀胱TCC转移至外阴的病例。
外阴病变的鉴别诊断,尤其是对于有既往泌尿道恶性肿瘤病史的女性,应包括转移性病变。