Fu K K, Newman H, Phillips T L
Radiology. 1975 Nov;117(2):425-31. doi: 10.1148/117.2.425.
Forty-two patients with recurrent nasopharyngeal carcinoma in the primary site and/or neck nodes were treated at the University of California, San Francisco, between 1940 and 1974. Sixty-nine per cent of the recurrences appeared within 3 years and 83% within 5 years after initial treatment. Retreatment included external radiotherapy and/or intercavitary radium or cobalt beads in the majority of cases. The actuarial survival rate was 41% at 5 years after first recurrence. Survival rates increased proportionally with increasing time between initial treatment and recurrence. There was no statistically significant difference in survival rates with respect to age, sex, race, or histology. Local soft-tissue or bone necrosis developed in 9 patients, but both conditions were tolerated well.
1940年至1974年间，加利福尼亚大学旧金山分校对42例原发部位和/或颈部淋巴结复发的鼻咽癌患者进行了治疗。69%的复发发生在初次治疗后的3年内，83%发生在5年内。在大多数病例中，再次治疗包括外照射放疗和/或腔内镭或钴珠植入。首次复发后5年的精算生存率为41%。生存率随着初次治疗与复发之间时间的增加而成比例提高。在年龄、性别、种族或组织学方面，生存率没有统计学上的显著差异。9例患者出现了局部软组织或骨坏死，但这两种情况均耐受性良好。
