Li Ai-ping, Hu Da-yi, Zhao Zhong, Ma Wen-lin, Zhang Xu, Mei Yun-qing, Liang Yu-lu, Zhao Xu-dong
Department of Cardiology, Shanghai Pulmonary Hospital of Tongji University, Shanghai 200433, China.
Zhonghua Yi Xue Za Zhi. 2006 Aug 22;86(31):2188-91.
To investigate the presence of depression in coronary artery bypass grafting (CABG) patients before and after the operation.
A questionnaire survey was conducted among 72 CABG patients, 21 of which, aged 65.30 +/- 1.15, underwent on-pump coronary artery bypass grafting (ONCAB) and 51 of which, aged 63.70 +/- 0.22, underwent off-pump CAB (OPCAB), using Beck Depression Inventory (BDI) one day before, and 3 and 6 months after the operation.
Depressive disorders occurred in 49.2% of the patients preoperatively and 26.7% of the patients 6 months after the operation. The mean pre-operative BDI score was 5.77, and the post-operative BDI scores 3 and 6 months after operation were 4.12 and 3.06 respectively. At different post-operative time points the BDI scores of the depressive group were all lower than those of the non-depressive group, however, there was still a trend of lowering of BDI scores in the latter group. There were more patients who failed to resume their original work and more patients with angina and hypertension in the depression group. The proportion of females after operation was higher in the depression group. There was no significant difference in BDI score between the ONCAB and OPCAB groups both pre- and post-operatively.
Depression at different degrees exists before CABG and can be improved post-operatively. Pre-operative BDI score is predictor of post-operative psychological outcome.
调查冠状动脉搭桥术(CABG)患者手术前后抑郁症的发生情况。
对72例CABG患者进行问卷调查,其中21例(年龄65.30±1.15岁)接受体外循环冠状动脉搭桥术(ONCAB),51例(年龄63.70±0.22岁)接受非体外循环冠状动脉搭桥术(OPCAB),分别在术前1天、术后3个月和6个月使用贝克抑郁量表(BDI)进行评估。
术前49.2%的患者出现抑郁障碍,术后6个月为26.7%。术前BDI平均评分为5.77,术后3个月和6个月的BDI评分分别为4.12和3.06。在术后不同时间点,抑郁组的BDI评分均低于非抑郁组,不过非抑郁组的BDI评分仍有下降趋势。抑郁组中未能恢复原工作的患者更多,心绞痛和高血压患者也更多。抑郁组术后女性比例更高。ONCAB组和OPCAB组术前及术后的BDI评分无显著差异。
CABG术前存在不同程度的抑郁,术后可改善。术前BDI评分是术后心理结局的预测指标。