Nergårdh Anna K, Rosenqvist Mårten, Frick Mats
Department of Cardiology, Karolinska Institute at Stockholm South Hospital, Stockholm, Sweden.
Int J Cardiol. 2007 Jun 25;119(1):95-100. doi: 10.1016/j.ijcard.2006.08.007. Epub 2006 Oct 24.
To evaluate if self-limited episodes of atrial fibrillation after DC cardioversion predict recurrence of persistent atrial fibrillation. To evaluate the incidence and duration of such episodes as well as their change over time.
Consecutive patients with persistent atrial fibrillation, scheduled for direct current cardioversion were prospectively included in the study. Ambulatory ECG Holter monitoring (24 h) was performed one, three and 6 weeks after successful cardioversion.
A total of 84 patients were prospectively included in the study. Sinus rhythm was restored in 74 patients (88%). At 6 weeks of follow-up 40 patients out of 74 (54%) had sinus rhythm, and 34 patients (46%) had relapsed into persistent atrial fibrillation. Eight out of these 34 patients (24%) had bursts of atrial fibrillation at their first Holter recording, compared to 12 patients out of 40 (30%) in sinus rhythm at 6 weeks (p>0.05). On the first, second and third Holter recording 21 patients out of 51 (41%), 21 patients out of 43 (49%) and 15 out of 40 patients (38%) had self-limited bursts of atrial fibrillation, respectively. The incidence or duration of episodes did not vary over time during the 6 weeks of follow-up.
In patients successfully converted to sinus rhythm self-limited bursts of atrial fibrillation do not predict recurrence of persistent atrial fibrillation during 6 weeks of follow up. Brief self-limited episodes of atrial fibrillation are common, and the incidence and duration of such episodes are constant during a 6 weeks period after DC cardioversion.
评估直流电复律后房颤自限性发作是否可预测持续性房颤复发。评估此类发作的发生率、持续时间及其随时间的变化。
将计划进行直流电复律的持续性房颤连续患者前瞻性纳入研究。在成功复律后1周、3周和6周进行动态心电图Holter监测(24小时)。
共有84例患者前瞻性纳入研究。74例患者(88%)恢复窦性心律。在6周随访时,74例患者中有40例(54%)维持窦性心律,34例患者(46%)复发为持续性房颤。这34例患者中有8例(24%)在首次Holter记录时有房颤发作,而6周时窦性心律的40例患者中有12例(30%)出现房颤发作(p>0.05)。在首次、第二次和第三次Holter记录中,51例患者中有21例(41%)、43例患者中有21例(49%)以及40例患者中有15例(38%)分别出现房颤自限性发作。在6周随访期间,发作的发生率或持续时间未随时间变化。
在成功转为窦性心律的患者中,房颤自限性发作在6周随访期间不能预测持续性房颤复发。短暂的房颤自限性发作很常见,且在直流电复律后的6周内,此类发作的发生率和持续时间保持不变。