Lou Li, Cong Xin-Li, Yu Guo-Fang, Li Ji-Chang, Ma Yu-Xiang
Department of Ultrasound, Shandong Medical Imaging Research Institute, Shandong University, Jinan 250021, China.
Eur J Radiol. 2007 Jan;61(1):154-7. doi: 10.1016/j.ejrad.2006.08.022. Epub 2006 Oct 24.
For women with breast cancer, the contralateral breast is at high risk. The bilateral cancers may be synchronous or metachronous. If the bilateral breast cancers have similar ultrasonography (US) appearances, the US findings of the first breast cancer (index cancer) might lead to early detection of the contralateral cancer. The purpose of this study was to identify the US characteristics of bilateral breast cancer and to determine whether bilateral breast cancers have similar US appearances and whether the US findings for one breast cancer might be predictive of the contralateral breast cancer.
We retrospectively reviewed the US manifestations of 58 patients with surgically proven bilateral primary breast cancer and compared the contralateral cancer with the index cancer by evaluation the margin, shape, inside echoes, posterior attenuation, calcification and color flow signals of 58 lesion pairs to investigate whether the bilateral breast cancers have similar US appearances.
Bilateral primary breast cancers were more located in upper outer quadrant, frequently spiculation, taller than wide shape, with irregular margin, heterogeneous internal echo and acoustic shadowing, containing microcalcification and abundant color flow signals. The most common US appearances were taller than wide shape (75.0%, 87/116), irregular margins (79.3%, 92/116) and heterogeneous internal echo (86.2%, 100/116). Of the total 58 lesion pairs, 18 (31.0%) pairs had similar US characteristics, whereas 40 (69.0%) pairs had different US characteristics.
US signs of the index cancer do not indicate the most likely appearance of the second cancer in the contralateral breast. Evaluation of the contralateral cancer should be performed without regard for the US findings for the index cancer.
对于乳腺癌女性患者，对侧乳房处于高风险状态。双侧癌症可能是同时性的或异时性的。如果双侧乳腺癌具有相似的超声（US）表现，那么首个乳腺癌（索引癌）的超声检查结果可能会促使对侧癌症的早期发现。本研究的目的是确定双侧乳腺癌的超声特征，并确定双侧乳腺癌是否具有相似的超声表现，以及一个乳腺癌的超声检查结果是否可预测对侧乳腺癌。
我们回顾性分析了58例经手术证实为双侧原发性乳腺癌患者的超声表现，并通过评估58对病灶的边界、形态、内部回声、后方衰减、钙化及彩色血流信号，将对侧癌与索引癌进行比较，以研究双侧乳腺癌是否具有相似的超声表现。
双侧原发性乳腺癌多位于外上象限，常见毛刺征，形态多为高大于宽，边界不规则，内部回声不均匀且有后方声影，伴有微钙化及丰富的彩色血流信号。最常见的超声表现为高大于宽（75.0%，87/116）、边界不规则（79.3%，92/116）及内部回声不均匀（86.2%，100/116）。在总共58对病灶中，18对（占31.0%）具有相似的超声特征，而40对（占6%.0%）具有不同的超声特征。
索引癌的超声征象并不能提示对侧乳房第二个癌症最可能的表现。对侧癌症的评估不应受索引癌超声检查结果的影响。
