肯尼亚无症状阴道感染的女性性工作者的阴道内行为与细菌性阴道病之间的关联。

Associations between intravaginal practices and bacterial vaginosis in Kenyan female sex workers without symptoms of vaginal infections.

作者信息

Hassan Wisal M, Lavreys Ludo, Chohan Vrasha, Richardson Barbra A, Mandaliya Kishorchandra, Ndinya-Achola Jeckoniah O, Kiarie James, Jaoko Walter, Holmes King K, McClelland R Scott

机构信息

Department of Epidemiology, University of Washington, Seattle, Washington, USA.

出版信息

Sex Transm Dis. 2007 Jun;34(6):384-8. doi: 10.1097/01.olq.0000243624.74573.63.

DOI:10.1097/01.olq.0000243624.74573.63

PMID:17065846

Abstract

BACKGROUND

Bacterial vaginosis (BV) is highly prevalent among African women and has been associated with adverse pregnancy outcomes, sexually transmitted diseases, and HIV-1.

GOAL

The goal of this study was to analyze the relationship among intravaginal practices, bathing, and BV.

STUDY DESIGN

The authors conducted a cross-sectional study of HIV-1-seronegative Kenyan female sex workers without symptoms of vaginal infections.

RESULTS

Of 237 women enrolled, 206 (87%) reported vaginal washing using either a finger or cloth. Increasing frequency of vaginal washing was associated with a higher likelihood of BV (chi(2) test for trend, P = 0.05). In multivariate analysis, vaginal lubrication with petroleum jelly (odds ratio [OR] = 2.8, 95% confidence interval [CI] = 1.4-5.6), lubrication with saliva (OR = 2.3, 95% CI = 1.1-4.8), and bathing less than the median for the cohort (14 times/week; OR = 4.6, 95% CI = 1.2-17.5) were associated with a significantly higher likelihood of BV.

CONCLUSIONS

Modification of intravaginal and general hygiene practices should be evaluated as potential strategies for reducing the risk of BV.

摘要

背景

细菌性阴道病（BV）在非洲女性中高度流行，且与不良妊娠结局、性传播疾病及HIV-1感染有关。

目的

本研究旨在分析阴道内操作、沐浴与BV之间的关系。

研究设计

作者对无症状性阴道感染的HIV-1血清阴性肯尼亚女性性工作者进行了一项横断面研究。

结果

在纳入的237名女性中，206名（87%）报告使用手指或布进行阴道冲洗。阴道冲洗频率增加与BV发生可能性较高相关（趋势χ²检验，P = 0.05）。多因素分析中，使用凡士林润滑阴道（比值比[OR]=2.8，95%置信区间[CI]=1.4 - 5.6）、使用唾液润滑（OR = 2.3，95% CI = 1.1 - 4.8）以及沐浴次数少于队列中位数（每周14次；OR = 4.6，95% CI = 1.2 - 17.5）与BV发生可能性显著较高相关。