Hassan Wisal M, Lavreys Ludo, Chohan Vrasha, Richardson Barbra A, Mandaliya Kishorchandra, Ndinya-Achola Jeckoniah O, Kiarie James, Jaoko Walter, Holmes King K, McClelland R Scott
Department of Epidemiology, University of Washington, Seattle, Washington, USA.
Sex Transm Dis. 2007 Jun;34(6):384-8. doi: 10.1097/01.olq.0000243624.74573.63.
Bacterial vaginosis (BV) is highly prevalent among African women and has been associated with adverse pregnancy outcomes, sexually transmitted diseases, and HIV-1.
The goal of this study was to analyze the relationship among intravaginal practices, bathing, and BV.
The authors conducted a cross-sectional study of HIV-1-seronegative Kenyan female sex workers without symptoms of vaginal infections.
Of 237 women enrolled, 206 (87%) reported vaginal washing using either a finger or cloth. Increasing frequency of vaginal washing was associated with a higher likelihood of BV (chi(2) test for trend, P = 0.05). In multivariate analysis, vaginal lubrication with petroleum jelly (odds ratio [OR] = 2.8, 95% confidence interval [CI] = 1.4-5.6), lubrication with saliva (OR = 2.3, 95% CI = 1.1-4.8), and bathing less than the median for the cohort (14 times/week; OR = 4.6, 95% CI = 1.2-17.5) were associated with a significantly higher likelihood of BV.
Modification of intravaginal and general hygiene practices should be evaluated as potential strategies for reducing the risk of BV.
细菌性阴道病（BV）在非洲女性中高度流行，且与不良妊娠结局、性传播疾病及HIV-1感染有关。
本研究旨在分析阴道内操作、沐浴与BV之间的关系。
作者对无症状性阴道感染的HIV-1血清阴性肯尼亚女性性工作者进行了一项横断面研究。
在纳入的237名女性中，206名（87%）报告使用手指或布进行阴道冲洗。阴道冲洗频率增加与BV发生可能性较高相关（趋势χ²检验，P = 0.05）。多因素分析中，使用凡士林润滑阴道（比值比[OR]=2.8，95%置信区间[CI]=1.4 - 5.6）、使用唾液润滑（OR = 2.3，95% CI = 1.1 - 4.8）以及沐浴次数少于队列中位数（每周14次；OR = 4.6，95% CI = 1.2 - 17.5）与BV发生可能性显著较高相关。
应评估改变阴道内及一般卫生习惯作为降低BV风险的潜在策略。
