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在赫尔辛基,非糖尿病患者和糖尿病患者的大截肢发生率均有所下降。

Major amputation incidence decreases both in non-diabetic and in diabetic patients in Helsinki.

作者信息

Eskelinen E, Eskelinen A, Albäck A, Lepäntalo M

机构信息

Department of Vascular Surgery, Helsinki University Central Hospital, Helsinki, Finland.

出版信息

Scand J Surg. 2006;95(3):185-9. doi: 10.1177/145749690609500311.

Abstract

BACKGROUND AND AIMS

The aim of the study was to assess the changes in diabetes-related lower extremity amputations and to compare it with the development of amputations for critical leg ischaemia in patients without diabetes.

MATERIAL AND METHODS

Clinical records of 1094 patients undergoing major lower limb amputations for vascular disease in the town of Helsinki during 13 years from 1990 to 2002 were analyzed retrospectively. Data concerning patient factors, diagnosis, existence of diabetes and amputation level were recorded. The study period was divided into three parts (1990-1994, 1995-1998 and 1999-2002) and results were compared between diabetic and nondiabetic vascular amputees during these time periods.

RESULTS

From 1990 through 2002, 561 of patients undergoing major lower limb amputation had diabetes mellitus. The overall incidence of major amputations of diabetics reduced from the first time period to the last period by 23%. At the same time, the incidence of amputations in non-diabetic patient group decreased 40%. If the incidence rate for amputations is expressed per million individuals with diabetes, 33% decrease was observed during the study period.

CONCLUSIONS

The decrease in major amputation rates among diabetic as well as non-diabetic patients can be attributed to the increased interest in amputation prevention, with a contribution by vascular surgeons being made in both groups.

摘要

背景与目的

本研究旨在评估糖尿病相关下肢截肢的变化情况,并将其与非糖尿病患者严重下肢缺血性截肢的发展情况进行比较。

材料与方法

回顾性分析了1990年至2002年这13年间在赫尔辛基市因血管疾病接受下肢大截肢手术的1094例患者的临床记录。记录了患者因素、诊断、糖尿病的存在情况以及截肢水平等数据。研究期间分为三个阶段(1990 - 1994年、1995 - 1998年和1999 - 2002年),并比较了这些时间段内糖尿病和非糖尿病血管性截肢患者的结果。

结果

1990年至2002年期间,接受下肢大截肢手术的患者中有561例患有糖尿病。糖尿病患者大截肢的总体发生率从第一个时间段到最后一个时间段下降了23%。与此同时,非糖尿病患者组的截肢发生率下降了40%。如果按每百万糖尿病患者计算截肢发生率,在研究期间观察到下降了33%。

结论

糖尿病患者和非糖尿病患者大截肢率的下降可归因于对截肢预防的关注度增加,两组中血管外科医生都做出了贡献。

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