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热带痉挛性截瘫/人嗜T淋巴细胞病毒I型相关脊髓病(TSP/HAM)诊断标准提案。

Proposal for diagnostic criteria of tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM).

作者信息

De Castro-Costa Carlos M, Araújo Abelardo Q C, Barreto Márcio M, Takayanagui Osvaldo M, Sohler Marzia P, da Silva Eduardo L M, de Paula Sônia M B, Ishak Ricardo, Ribas João G R, Rovirosa Luis C, Carton Herwig, Gotuzzo Eduardo, Hall William W, Montano Silvia, Murphy Edward L, Oger Joel, Remondegui Carlos, Taylor Graham P

机构信息

Departamento de Fisiologia e Farmacologia, Universidade Federal do Ceará, Rodolfo Teófilo, 60430-270, Fortaleza-CE, Brazil.

出版信息

AIDS Res Hum Retroviruses. 2006 Oct;22(10):931-5. doi: 10.1089/aid.2006.22.931.

Abstract

After the first description of TSP/HAM in 1985 and the elaboration of WHO's diagnostic criteria in 1988, the experience of the professionals in this field has increased so that a critical reappraisal of these diagnostic guidelines was considered timely. Brazilian neurologists and observers from other countries met recently to discuss and propose a modified model for diagnosing TSP/HAM with levels of ascertainment as definite, probable, and possible, according to myelopathic symptoms, serological findings, and/or detection of HTLV-I DNA and exclusion of other disorders.

摘要

1985年首次描述热带痉挛性截瘫/人类嗜T淋巴细胞病毒I型相关脊髓病(TSP/HAM),1988年详细阐述了世界卫生组织的诊断标准之后,该领域专业人员的经验不断增加,因此认为对这些诊断指南进行批判性重新评估是适时的。巴西神经学家和其他国家的观察人员最近举行会议,根据脊髓病症状、血清学检查结果和/或检测人类嗜T淋巴细胞病毒I型(HTLV-I)DNA并排除其他疾病,讨论并提出了一个用于诊断TSP/HAM的改良模型,确定了确诊、可能、疑似三个诊断级别。

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