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从突变体分析到基因工程

From analysis of mutants to genetic engineering.

作者信息

von Wettstein Diter

机构信息

Department of Crop and Soil Sciences, School of Molecular Biosciences and Center for Integrated Biotechnology, Washington State University, Pullman, WA 99164-6420, USA.

出版信息

Annu Rev Plant Biol. 2007;58:1-19. doi: 10.1146/annurev.arplant.58.032806.104003.

DOI:10.1146/annurev.arplant.58.032806.104003
PMID:17067283
Abstract

This chapter describes the research of developing transgenic barley for synthesis of recombinant proteins with practical significance and of metabolic engineering of proanthocyanidin-free barley. The results were obtained by graduate students, postdoctoral researchers, and visiting scientists at the Carlsberg Laboratory from 1972-1996 and during the past ten years at Washington State University. It is written in appreciation of their enthusiasm, skill, and perseverance.

摘要

本章描述了开发用于合成具有实际意义的重组蛋白的转基因大麦以及无原花青素大麦代谢工程的研究。这些结果是由嘉士伯实验室1972年至1996年期间的研究生、博士后研究人员和访问科学家以及华盛顿州立大学过去十年的研究人员获得的。撰写本文是为了感谢他们的热情、技能和毅力。

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Targeted modification of wheat grain protein to reduce the content of celiac causing epitopes.靶向修饰小麦籽粒蛋白以降低麦胶蛋白致敏性表位含量。
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Functional characterization of barley betaglucanless mutants demonstrates a unique role for CslF6 in (1,3;1,4)-β-D-glucan biosynthesis.大麦葡聚糖缺失突变体的功能表征表明 CslF6 在(1,3;1,4)-β-D-葡聚糖生物合成中的独特作用。
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