Shi Dong, Meng Huan-xin, Xu Li, Zhang Li, Chen Zhi-bin, Feng Xiang-hui
Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2006 Jul;41(7):401-2.
To determine the serum levels of lipid and glucose in patients with periodontitis.
The patients with aggressive periodontitis (AgP, n = 117) and chronic periodontitis (CP, n = 40) and healthy controls (n = 37) were recruited. Peripheral blood sample was obtained from each subject by venipuncture. Serum chemistry variables including total cholesterol, triglycerides, and fasting glucose were analyzed by biochemical analyzer.
The average serum levels of triglycerides and glucose of the patients with AgP [(1.09 +/- 0.79) mmol/L and (5.07 +/- 0.66) mmol/L] were both significantly higher than those of the control group [(0.94 +/- 0.28) mmol/L and (4.62 +/- 0.64) mmol/L], P < 0.05. Higher serum levels of total cholesterol and glucose were also observed in patients with CP [(4.61 +/- 1.23) mmol/L and (5.40 +/- 1.01) mmol/L] compared with controls [(4.49 +/- 0.78) mmol/L and (4.62 +/- 0.64) mmol/L], P < 0.05. Serum level of total cholesterol in AgP group was positively associated with percentage of severe sites (r = 0.25, P < 0.01).
Patients with periodontitis may have altered serum lipid and glucose levels compared with controls.
测定牙周炎患者的血脂和血糖水平。
招募侵袭性牙周炎患者（AgP，n = 117）、慢性牙周炎患者（CP，n = 40）和健康对照者（n = 37）。通过静脉穿刺采集每位受试者的外周血样本。使用生化分析仪分析血清化学变量，包括总胆固醇、甘油三酯和空腹血糖。
AgP患者的甘油三酯和血糖平均血清水平[分别为(1.09±0.79) mmol/L和(5.07±0.66) mmol/L]均显著高于对照组[分别为(0.94±0.28) mmol/L和(4.62±0.64) mmol/L]，P<0.05。与对照组[分别为(4.49±0.78) mmol/L和(4.62±0.64) mmol/L]相比，CP患者的总胆固醇和血糖血清水平也更高[(4.61±1.23) mmol/L和(5.40±1.01) mmol/L]，P<0.05。AgP组的总胆固醇血清水平与重度位点百分比呈正相关（r = 0.25，P<0.01）。
与对照组相比，牙周炎患者的血清脂质和血糖水平可能发生了改变。
