Rogers Lee C, Frykberg Robert G
Saint Vincent Catholic Medical Centers, 152-11 89(th) Avenue, New York, NY 11432, USA.
Clin Podiatr Med Surg. 2006 Oct;23(4):769-75, vii-i. doi: 10.1016/j.cpm.2006.01.007.
The infected or ulcerated diabetic foot is a suitable environment for Clostridium tetani. Tetanus intoxication as a result of foot ulcer has been described in the literature. Immunopathy, vasculopathy, and ulceration place the diabetic patient at risk for developing tetanus. Of diabetic patients who contract generalized tetanus in the United States, foot ulcer or gangrene are responsible for 25% of cases. Patients who have diabetic wounds should receive tetanus prophylaxis. The prophylaxis should follow the "tetanus-prone" wound recommendations as set by the Centers for Disease Control and Prevention Advisory Committee on Immunization Practices.
感染或溃疡的糖尿病足是破伤风梭菌生长的适宜环境。足部溃疡导致破伤风中毒的情况在文献中已有描述。免疫病变、血管病变和溃疡使糖尿病患者有发生破伤风的风险。在美国，患全身性破伤风的糖尿病患者中，足部溃疡或坏疽占25%的病例。有糖尿病伤口的患者应接受破伤风预防。预防措施应遵循美国疾病控制与预防中心免疫实践咨询委员会制定的“易患破伤风”伤口的建议。
