• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

CRH mediates inflammation induced by lipopolysaccharide in human adult epidermal keratinocytes.

作者信息

Zbytek Blazej, Slominski Andrzej T

出版信息

J Invest Dermatol. 2007 Mar;127(3):730-2. doi: 10.1038/sj.jid.5700607. Epub 2006 Oct 19.

DOI:10.1038/sj.jid.5700607
PMID:17068474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1839835/
Abstract
摘要

相似文献

1
CRH mediates inflammation induced by lipopolysaccharide in human adult epidermal keratinocytes.促肾上腺皮质激素释放激素介导脂多糖在成人人类表皮角质形成细胞中诱导的炎症反应。
J Invest Dermatol. 2007 Mar;127(3):730-2. doi: 10.1038/sj.jid.5700607. Epub 2006 Oct 19.
2
The synergistic activities of the combination of tumour necrosis factor-α, interleukin-17A and interferon-γ in epidermal keratinocytes.肿瘤坏死因子-α、白细胞介素-17A和干扰素-γ联合作用于表皮角质形成细胞的协同活性。
Br J Dermatol. 2018 Aug;179(2):496-498. doi: 10.1111/bjd.16443. Epub 2018 May 11.
3
Corticotropin-releasing hormone induces keratinocyte differentiation in the adult human epidermis.促肾上腺皮质激素释放激素诱导成人人类表皮中的角质形成细胞分化。
J Cell Physiol. 2005 Apr;203(1):118-26. doi: 10.1002/jcp.20209.
4
Staphylococcus aureus infection of epidermal keratinocytes promotes expression of innate antimicrobial peptides.表皮角质形成细胞的金黄色葡萄球菌感染促进天然抗菌肽的表达。
Infect Immun. 2005 Aug;73(8):5241-4. doi: 10.1128/IAI.73.8.5241-5244.2005.
5
Corticotropin-releasing hormone triggers differentiation in HaCaT keratinocytes.促肾上腺皮质激素释放激素触发人永生化角质形成细胞(HaCaT)分化。
Br J Dermatol. 2005 Mar;152(3):474-80. doi: 10.1111/j.1365-2133.2005.06217.x.
6
MHC class II antigen expression is not induced on murine epidermal keratinocytes by interferon-gamma alone or in combination with tumour necrosis factor-alpha.单独的γ干扰素或其与α肿瘤坏死因子联合使用时,不会诱导小鼠表皮角质形成细胞表达II类主要组织相容性复合体抗原。
Immunology. 1989 Jan;66(1):100-5.
7
The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation.衔接蛋白 FADD 可保护体内表皮角质形成细胞免于发生坏死性凋亡,进而预防皮肤炎症。
Immunity. 2011 Oct 28;35(4):572-82. doi: 10.1016/j.immuni.2011.08.014. Epub 2011 Oct 13.
8
Corticotropin-releasing hormone (CRH) downregulates interleukin-18 expression in human HaCaT keratinocytes by activation of p38 mitogen-activated protein kinase (MAPK) pathway.促肾上腺皮质激素释放激素(CRH)通过激活p38丝裂原活化蛋白激酶(MAPK)途径下调人HaCaT角质形成细胞中白细胞介素-18的表达。
J Invest Dermatol. 2005 Apr;124(4):751-5. doi: 10.1111/j.0022-202X.2005.23656.x.
9
The epidermal growth factor receptor is a regulator of epidermal complement component expression and complement activation.表皮生长因子受体是表皮补体成分表达和补体激活的调节剂。
J Immunol. 2014 Apr 1;192(7):3355-64. doi: 10.4049/jimmunol.1302305. Epub 2014 Mar 3.
10
Corticotropin releasing factor receptor 1 (CRF1) and CRF2 agonists exert an anti-inflammatory effect during the early phase of inflammation suppressing LPS-induced TNF-alpha release from macrophages via induction of COX-2 and PGE2.促肾上腺皮质激素释放因子受体1(CRF1)和CRF2激动剂在炎症早期发挥抗炎作用,通过诱导环氧化酶-2(COX-2)和前列腺素E2(PGE2)抑制脂多糖(LPS)诱导的巨噬细胞肿瘤坏死因子-α(TNF-α)释放。
J Cell Physiol. 2007 Mar;210(3):774-83. doi: 10.1002/jcp.20900.

引用本文的文献

1
Neuro-immuno-endocrinology of the skin: how environment regulates body homeostasis.皮肤的神经-免疫-内分泌学:环境如何调节身体稳态。
Nat Rev Endocrinol. 2025 Apr 22. doi: 10.1038/s41574-025-01107-x.
2
The brain-skin axis in vitiligo.白癜风的脑-皮肤轴。
Arch Dermatol Res. 2024 Sep 6;316(8):607. doi: 10.1007/s00403-024-03362-w.
3
Neuroendocrine signaling in the skin with a special focus on the epidermal neuropeptides.皮肤中的神经内分泌信号转导,特别关注表皮神经肽。
Am J Physiol Cell Physiol. 2022 Dec 1;323(6):C1757-C1776. doi: 10.1152/ajpcell.00147.2022. Epub 2022 Nov 1.
4
Vitamin D Signaling in Psoriasis: Pathogenesis and Therapy.维生素 D 在银屑病中的信号转导:发病机制与治疗。
Int J Mol Sci. 2022 Aug 2;23(15):8575. doi: 10.3390/ijms23158575.
5
A Systematic Review of Keratinocyte Secretions: A Regenerative Perspective.角质形成细胞分泌物的系统评价:再生视角。
Int J Mol Sci. 2022 Jul 19;23(14):7934. doi: 10.3390/ijms23147934.
6
The Brain-Skin Axis in Psoriasis-Psychological, Psychiatric, Hormonal, and Dermatological Aspects.银屑病的脑-皮肤轴:心理、精神、激素和皮肤学方面。
Int J Mol Sci. 2022 Jan 8;23(2):669. doi: 10.3390/ijms23020669.
7
Pathogenesis of psoriasis in the "omic" era. Part I. Epidemiology, clinical manifestation, immunological and neuroendocrine disturbances.“组学”时代银屑病的发病机制。第一部分。流行病学、临床表现、免疫及神经内分泌紊乱
Postepy Dermatol Alergol. 2020 Apr;37(2):135-153. doi: 10.5114/ada.2020.94832. Epub 2020 May 5.
8
New effects of caffeine on corticotropin-releasing hormone (CRH)-induced stress along the intrafollicular classical hypothalamic-pituitary-adrenal (HPA) axis (CRH-R1/2, IP -R, ACTH, MC-R2) and the neurogenic non-HPA axis (substance P, p75 and TrkA) in ex vivo human male androgenetic scalp hair follicles.咖啡因对卵泡内经典下丘脑-垂体-肾上腺轴(CRH-R1/2、IP-R、ACTH、MC-R2)和神经源性非 HPA 轴(P 物质、p75 和 TrkA)诱导的应激的新影响在离体人雄性雄激素性头皮毛囊中。
Br J Dermatol. 2021 Jan;184(1):96-110. doi: 10.1111/bjd.19115. Epub 2020 Jun 24.
9
Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders.肾上腺外糖皮质激素生物合成:对自身免疫和炎症性疾病的影响。
Genes Immun. 2020 May;21(3):150-168. doi: 10.1038/s41435-020-0096-6. Epub 2020 Mar 23.
10
On the role of skin in the regulation of local and systemic steroidogenic activities.皮肤在局部和全身类固醇生成活性调节中的作用。
Steroids. 2015 Nov;103:72-88. doi: 10.1016/j.steroids.2015.04.006. Epub 2015 May 16.

本文引用的文献

1
Characterization of a ultraviolet B-induced corticotropin-releasing hormone-proopiomelanocortin system in human melanocytes.人黑素细胞中紫外线B诱导的促肾上腺皮质激素释放激素-阿黑皮素原系统的特征
Mol Endocrinol. 2006 Oct;20(10):2539-47. doi: 10.1210/me.2006-0116. Epub 2006 Jun 1.
2
Corticotropin releasing hormone and the skin.促肾上腺皮质激素释放激素与皮肤。
Front Biosci. 2006 Sep 1;11:2230-48. doi: 10.2741/1966.
3
The role of corticotropin-releasing hormone in immune-mediated cutaneous inflammatory disease.促肾上腺皮质激素释放激素在免疫介导的皮肤炎症性疾病中的作用。
Exp Dermatol. 2006 Mar;15(3):143-53. doi: 10.1111/j.1600-0625.2006.00382.x.
4
CRH functions as a growth factor/cytokine in the skin.促肾上腺皮质激素释放激素在皮肤中作为一种生长因子/细胞因子发挥作用。
J Cell Physiol. 2006 Mar;206(3):780-91. doi: 10.1002/jcp.20530.
5
Distinct strains of Propionibacterium acnes induce selective human beta-defensin-2 and interleukin-8 expression in human keratinocytes through toll-like receptors.痤疮丙酸杆菌的不同菌株通过Toll样受体诱导人角质形成细胞中选择性表达人β-防御素-2和白细胞介素-8。
J Invest Dermatol. 2005 May;124(5):931-8. doi: 10.1111/j.0022-202X.2005.23705.x.
6
Corticotropin-releasing hormone contributes to the peripheral inflammatory response in experimental autoimmune encephalomyelitis.促肾上腺皮质激素释放激素在实验性自身免疫性脑脊髓炎中参与外周炎症反应。
J Immunol. 2005 May 1;174(9):5407-13. doi: 10.4049/jimmunol.174.9.5407.
7
CRH stimulation of corticosteroids production in melanocytes is mediated by ACTH.促肾上腺皮质激素释放激素(CRH)对黑素细胞中皮质类固醇生成的刺激作用是由促肾上腺皮质激素(ACTH)介导的。
Am J Physiol Endocrinol Metab. 2005 Apr;288(4):E701-6. doi: 10.1152/ajpendo.00519.2004. Epub 2004 Nov 30.
8
Mast cells as targets of corticotropin-releasing factor and related peptides.肥大细胞作为促肾上腺皮质激素释放因子及相关肽的作用靶点。
Trends Pharmacol Sci. 2004 Nov;25(11):563-8. doi: 10.1016/j.tips.2004.09.007.
9
Corticotropin-releasing hormone induces keratinocyte differentiation in the adult human epidermis.促肾上腺皮质激素释放激素诱导成人人类表皮中的角质形成细胞分化。
J Cell Physiol. 2005 Apr;203(1):118-26. doi: 10.1002/jcp.20209.
10
Corticotropin-releasing hormone stimulates NF-kappaB in human epidermal keratinocytes.促肾上腺皮质激素释放激素刺激人表皮角质形成细胞中的核因子κB。
J Endocrinol. 2004 Jun;181(3):R1-7. doi: 10.1677/joe.0.181r001.