Dabrowski A, Kolodziej P, Krupienicz A
Central Clinical Hospital, Military School of Medicine, Warsaw, Poland.
Pacing Clin Electrophysiol. 1991 Feb;14(2 Pt 2):366-9. doi: 10.1111/j.1540-8159.1991.tb05123.x.
The relation of inducible ventricular tachycardia (VT) to QT interval duration of ventricular paced rhythm has not been evaluated. To clarify this relation we measured corrected QT interval duration (QTc) during sinus rhythm and QT interval duration during ventricular paced rhythm (QT-V) in patients with coronary artery disease without (non-VT group = group B) and with inducible VT (VT group = group A). Duration of QT-V was greater in the VT group (n = 20) compared with non-VT group (n = 20) during ventricular pacing at cycle lengths of 600 ms (424 +/- 26 vs 396 +/- 19 ms, P less than 0.01), of 500 ms (407 +/- 20 vs 383 +/- 21 ms, P less than 0.01), and of 400 ms (390 +/- 21 vs 362 +/- 17 ms, P less than 0.001). During sinus rhythm the mean values of QTc were similar in both groups (408 +/- 25 vs 413 +/- 20 ms, NS). During ventricular stimulation the percentage of patients with values of QT-V exceeding 380 ms was 35% in non-VT group and 95% in VT group (P less than 0.01) at cycle length of 500 ms and 5% versus 60%, respectively, (P less than 0.01), at cycle length of 400 ms. Thus, a trend toward longer QT values of ventricular paced rhythm exists in patients with inducible VT.
可诱导性室性心动过速（VT）与心室起搏心律的QT间期持续时间之间的关系尚未得到评估。为了阐明这种关系，我们测量了冠心病患者在窦性心律期间的校正QT间期持续时间（QTc）以及在心室起搏心律期间的QT间期持续时间（QT-V），这些患者分为无诱导性VT组（非VT组 = B组）和有诱导性VT组（VT组 = A组）。在600毫秒的周期长度心室起搏期间，VT组（n = 20）的QT-V持续时间比非VT组（n = 20）更长（424±26对396±19毫秒，P<0.01）；在500毫秒时（407±20对383±21毫秒，P<0.01）；在400毫秒时（390±21对362±17毫秒，P<0.001）。在窦性心律期间，两组的QTc平均值相似（408±25对413±20毫秒，无显著性差异）。在心室刺激期间，在500毫秒的周期长度时，非VT组中QT-V值超过380毫秒的患者百分比为35%，VT组为95%（P<0.01）；在400毫秒的周期长度时，分别为5%和60%（P<0.01）。因此，有诱导性VT的患者存在心室起搏心律QT值更长的趋势。
