针对人类单核细胞表面标志物CD 14的单克隆抗体（RoMo-1）受体介导内吞作用的电子显微镜研究。
Electron microscopic study of receptor mediated endocytosis of a monoclonal antibody (RoMo-1) against the surface marker CD 14 of human monocytes.
作者信息
Jonas L, Schütt C, Neels P, Walzel H, Siegl E
机构信息
Electron Microscopic Centre, Wilhelm-Pieck-University of Rostock, GDR.
出版信息
Acta Histochem Suppl. 1990;39:339-44.
The internalization of the gold labelled monoclonal antibody RoMo-1 recognizing the CD 14 surface molecule of human monocytes was studied by electron microscopy. Monocyte enriched mononuclear cells (MNC) from the peripheral blood of healthy donors were incubated for 15, 30, 60, and 90 min with gold marked RoMo-1 in Eagle MEM at 37 degrees C. The process of internalization of RoMo-1 occurs as a receptor mediated endocytosis (RME), as described for other ligands.
通过电子显微镜研究了识别人类单核细胞CD 14表面分子的金标记单克隆抗体RoMo-1的内化过程。将来自健康供体外周血的富含单核细胞的单核细胞（MNC）在37℃下于伊格尔MEM中与金标记的RoMo-1孵育15、30、60和90分钟。如对其他配体所描述的那样，RoMo-1的内化过程以受体介导的内吞作用（RME）形式发生。
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