Alaya Akram, Belgith Mohsen, Jouini Riadh, Nouri Abdellatif, Najjar Mohamed Fadhel
Laboratoire de Biochimie-Toxicologie, CHU Monastir, Tunisie.
Prog Urol. 2006 Sep;16(4):474-80.
The clinical and laboratory characteristics of urolithiasis in Tunisian children have evolved continuously since the 1980s. This retrospective study defines the current status of urolithiasis in children in Tunisia.
All 104 children (age: 8-192 months) of our series were hospitalized for urolithiasis. A first-line metabolic, urine and plasma work-up was performed in 96 patients. Physical and chemical analysis of the stones was performed by stereomicroscopy and infrared spectroscopy, respectively. Statistical analysis of the results was performed with SPSS 11.0 software. The Chi-square test was used for comparison of percentages.
Our study shows a male predominance of urolithiasis with a sex ratio of 1.53. The clinical features were dominated by urinary tract infections (28.8%). Stones were situated in the upper tract in 75% of cases and the lower tract in 25% of cases. Urine culture was positive in 15 patients. Identification of the crystalline composition showed that whewellite was the most frequent crystalline species in children (80.0%) and infants (57.1%). Ammonium acid urate was more frequent in infants.
In this study, we observed changes in the epidemiological characteristics (bladder stones and infection stones) of urolithiasis in children over the last decade in Tunisia. The patient's age is an important factor that must be taken into account during aetiopathogenic work-up.
自20世纪80年代以来,突尼斯儿童尿路结石的临床和实验室特征一直在持续演变。这项回顾性研究确定了突尼斯儿童尿路结石的现状。
我们系列研究中的所有104名儿童(年龄:8 - 192个月)因尿路结石住院。对96名患者进行了一线代谢、尿液和血浆检查。分别通过体视显微镜和红外光谱对结石进行物理和化学分析。使用SPSS 11.0软件对结果进行统计分析。采用卡方检验比较百分比。
我们的研究显示尿路结石以男性为主,性别比为1.53。临床特征以尿路感染为主(28.8%)。75%的病例结石位于上尿路,25%的病例位于下尿路。15名患者的尿培养呈阳性。晶体成分鉴定显示,水草酸钙是儿童(80.0%)和婴儿(57.1%)中最常见的晶体种类。尿酸铵在婴儿中更为常见。
在本研究中,我们观察到突尼斯过去十年儿童尿路结石的流行病学特征(膀胱结石和感染性结石)发生了变化。在病因学检查过程中,患者年龄是一个必须考虑的重要因素。