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儿童内斜视的发病率及类型:一项基于人群的研究。

Incidence and types of childhood esotropia: a population-based study.

作者信息

Greenberg Amy E, Mohney Brian G, Diehl Nancy N, Burke James P

机构信息

Mayo Clinic College of Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.

出版信息

Ophthalmology. 2007 Jan;114(1):170-4. doi: 10.1016/j.ophtha.2006.05.072. Epub 2006 Oct 27.

DOI:10.1016/j.ophtha.2006.05.072
PMID:17070595
Abstract

OBJECTIVE

To describe the incidence and types of childhood esotropia in a defined population.

DESIGN

Retrospective population-based cohort.

PARTICIPANTS

All pediatric (<19 years of age) residents of Olmsted County, Minnesota, diagnosed with an esodeviation (> or =10 prism diopters) from January 1, 1985, through December 31, 1994.

METHODS

The medical records of all potential patients identified by the resources of the Rochester Epidemiology Project were reviewed.

MAIN OUTCOME MEASURES

Incidence and types of childhood esotropia.

RESULTS

Three hundred eighty-five cases of childhood esotropia were identified during the 10-year period, yielding an annual age- and gender-adjusted incidence of 111.0 (95% confidence interval, 99.9-122.1) per 100,000 patients younger than 19 years of age. This rate corresponds to a cumulative prevalence of approximately 2.0% of all children younger than 6 years, with a significant decrease in older ages (P<0.0001). Of the 385 study children, the specific forms and percentages of esotropia diagnosed were as follows: fully accommodative, 140 (36.4%); acquired nonaccommodative, 64 (16.6%); esotropia associated with an abnormal central nervous system, 44 (11.4%); partially accommodative, 39 (10.1%); congenital, 31 (8.1%); sensory, 25 (6.5%); paralytic, 25 (6.5%); undetermined, 13 (3.4%); and other, 4 (1.0%).

CONCLUSIONS

The incidence of childhood esotropia from this self-referred population-based study is comparable with prevalence rates reported among Western populations. Esotropia is most common during the first decade of life, with the accommodative and acquired nonaccommodative forms occurring most frequently. The congenital, sensory, and paralytic forms of childhood esotropia were less common in this population.

摘要

目的

描述特定人群中儿童内斜视的发病率及类型。

设计

基于人群的回顾性队列研究。

参与者

明尼苏达州奥尔姆斯特德县所有19岁以下被诊断为内斜(≥10棱镜度)的儿科居民,时间从1985年1月1日至1994年12月31日。

方法

查阅罗切斯特流行病学项目资源所识别出的所有潜在患者的病历。

主要观察指标

儿童内斜视的发病率及类型。

结果

在这10年期间共识别出385例儿童内斜视病例,年龄和性别调整后的年发病率为每10万名19岁以下患者中111.0例(95%置信区间为99.9 - 122.1)。该发病率相当于6岁以下所有儿童累计患病率约为2.0%,年长儿童患病率显著下降(P<0.0001)。在385名研究儿童中,诊断出的内斜视具体类型及百分比如下:完全调节性,140例(36.4%);后天非调节性,64例(16.6%);与中枢神经系统异常相关的内斜视,44例(11.4%);部分调节性,39例(10.1%);先天性,31例(8.1%);感觉性,25例(6.5%);麻痹性,25例(6.5%);未确定,13例(3.4%);其他,4例(1.0%)。

结论

这项基于自我转诊人群的研究中儿童内斜视的发病率与西方人群报告的患病率相当。内斜视在生命的第一个十年最为常见,调节性和后天非调节性类型最为频繁出现。该人群中儿童内斜视的先天性、感觉性和麻痹性类型较少见。

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