Watson R E, Stewart C
Department of Oral Diagnostic Sciences, College of Dentistry, University of Florida, Gainesville 32610.
Oral Surg Oral Med Oral Pathol. 1991 Mar;71(3):312-6. doi: 10.1016/0030-4220(91)90306-w.
Foreign bodies and tissue reactions to foreign materials are commonly encountered in the oral cavity. Exogenous materials most commonly causing foreign body reactions are metallic in origin (usually amalgam). Of the nonmetallic materials seen during biopsies, suture materials and vegetable matter are most often observed. Since many foodstuff foreign materials are unidentifiable histologically, common vegetables were experimentally implanted subcutaneously in rats to assess local host responses and to characterize the nature of these materials microscopically. The histologic characteristics of these vegetable foreign body reactions are detailed herein. The implanted materials correspond to reactions seen in human subjects.
口腔中经常会遇到异物以及机体对异物的组织反应。引起异物反应的外源性物质大多源于金属（通常是汞合金）。在活检中发现的非金属物质中，最常观察到的是缝合材料和植物性物质。由于许多食物中的异物在组织学上无法识别，因此将常见蔬菜实验性地皮下植入大鼠体内，以评估局部宿主反应并在显微镜下描述这些物质的性质。本文详细介绍了这些植物性异物反应的组织学特征。植入的物质与在人类受试者中观察到的反应一致。
