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社会剥夺与他汀类药物处方:一项使用英国新的全科医生“质量与结果框架”数据的横断面分析。

Social deprivation and statin prescribing: a cross-sectional analysis using data from the new UK general practitioner 'Quality and Outcomes Framework'.

作者信息

Ashworth M, Lloyd D, Smith R S, Wagner A, Rowlands G

机构信息

Department of General Practice and Primary Care, King's College London School of Medicine at Guy's, King's College and St Thomas' Hospitals, 5 Lambeth Walk, London SE11 6SP, UK.

出版信息

J Public Health (Oxf). 2007 Mar;29(1):40-7. doi: 10.1093/pubmed/fdl068. Epub 2006 Oct 27.

Abstract

We aimed to study the relationship between the prescribing of lipid-lowering medication, social deprivation and other general practice characteristics. We conducted a cross-sectional survey of all general practices in England, 2004-05. For each practice, the following variables were obtained: standardized cost and volume data for lipid-lowering medication, descriptors of general practices, Index of Multiple Deprivation, 2004, ethnicity data from the 2001 Census and Quality and Outcomes Framework data. A regression model was constructed which explained 34.5% of the variation in statin prescribing by general practitioners. The most powerful predictors were higher social deprivation, higher prevalence of coronary heart disease and achievement of cholesterol targets for diabetics. Negative regression coefficients were demonstrated for the proportion of elderly patients in the practice and, to a lesser extent, for the proportion of south Asian and Afro-Caribbean patients. In conclusion, contrary to previous local studies, we found that statin prescribing was higher in more deprived communities, even after adjustment for increased disease prevalence and practice variables associated with deprivation. Statin prescribing was also independently associated with success at achieving cholesterol targets in established disease (secondary prevention). However, our findings suggest under-prescribing of statins to the elderly and possibly also to ethnic minorities.

摘要

我们旨在研究降脂药物处方、社会剥夺与其他全科医疗特征之间的关系。我们于2004 - 2005年对英格兰所有全科医疗进行了一项横断面调查。对于每个医疗机构,获取了以下变量:降脂药物的标准化成本和用量数据、全科医疗描述符、2004年多重剥夺指数、2001年人口普查的种族数据以及质量与结果框架数据。构建了一个回归模型,该模型解释了全科医生他汀类药物处方差异的34.5%。最有力的预测因素是较高的社会剥夺程度、较高的冠心病患病率以及糖尿病患者胆固醇目标的达成情况。在医疗机构中,老年患者比例呈现负回归系数,南亚和非洲加勒比裔患者比例在较小程度上也呈现负回归系数。总之,与之前的局部研究相反,我们发现即使在对与剥夺相关的疾病患病率增加和医疗机构变量进行调整之后,他汀类药物在更贫困社区的处方率更高。他汀类药物处方还与既定疾病(二级预防)中胆固醇目标的实现独立相关。然而,我们的研究结果表明,他汀类药物在老年人以及可能在少数族裔中的处方不足。

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