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[以化脓性肉芽肿为表现的瘘管及深部感染:5例报告]

[Pyogenic granuloma revealing fistula and deep infection: five cases].

作者信息

Sparsa A, Bonnetblanc J-M, Roux C, Pinet C, Loustaud-Ratti V, Boulinguez S, Labrousse F, Vidal E, Bedane C

机构信息

Service de Dermatologie CHU Dupuytren, 2, avenue Martin-Luther-King, 87000 Limoges.

出版信息

Ann Dermatol Venereol. 2006 Oct;133(10):763-6. doi: 10.1016/s0151-9638(06)71039-0.

Abstract

BACKGROUND

Pyogenic granuloma, or botryomycosis, occurring after minor injury or scratching with a septic implement, is a rapidly growing benign inflammatory vascular tumour, often involving the skin or mucous membrane. We report 5 unusual cases of pyogenic granuloma revealing fistula tracking to foreign bodies such as a pace-maker or orthopaedic material, and deep infectious sites with fistula.

METHODS

This retrospective study included 5 men of average age 72.2 years over a period of 22 years (between 1981 and 2003). Clinical images were recorded and a diagnosis of botryomycosis was confirmed in all patients by histological analysis. Four patients presented suppuration. The time from initial clinical signs to diagnosis, presence of traumatic events, screening for microscopic organisms, response to systemic antibiotic therapy, recurrence and clinical features of botriomycosis were analysed.

RESULTS

All patients presented botryomycosis with fistula and suppuration revealing deep bone infection and in one patient, pace maker infection. Complete resolution of the lesions occurred after excision of foreign material and prolonged systemic antibiotic therapy.

CONCLUSION

We report the first series of botryomycosis revealed by fistula and showing deep infectious disease. Pyogenic granuloma is a well-known but rarely reported dermatologic condition.

摘要

背景

脓性肉芽肿,即葡萄状菌病,在轻微损伤或被化脓性器具刮擦后发生,是一种迅速生长的良性炎症性血管肿瘤,常累及皮肤或黏膜。我们报告了5例不寻常的脓性肉芽肿病例,这些病例显示瘘管追踪到诸如起搏器或骨科材料等异物以及伴有瘘管的深部感染部位。

方法

这项回顾性研究纳入了22年间(1981年至2003年)平均年龄72.2岁的5名男性。记录临床图像,所有患者均通过组织学分析确诊为葡萄状菌病。4例患者出现化脓。分析了从初始临床症状到诊断的时间、创伤事件的存在、微生物镜检筛查、全身抗生素治疗反应、复发情况以及葡萄状菌病的临床特征。

结果

所有患者均出现伴有瘘管和化脓的葡萄状菌病,显示深部骨感染,1例患者为起搏器感染。在切除异物并进行长时间全身抗生素治疗后,病变完全消退。

结论

我们报告了首例由瘘管揭示并显示深部感染疾病的葡萄状菌病系列病例。脓性肉芽肿是一种众所周知但很少报道的皮肤病。

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