Qin Rosie, Cohen Philip R
Department of Medicine, University of California San Diego, La Jolla, California.
Dermatol Online J. 2017 Mar 15;23(3):13030/qt0p22m4dg.
Bullous impetigo is a superficial skininfection caused by Staphylococcus aureus (S.aureus). Pyogenic granuloma is a common benigntumor frequently associated with prior trauma.Bullous impetigo and pyogenic granuloma may occurin pregnant women.
The features of a pregnant womanwith pyogenic granuloma and bullous impetigoconcurrently present in a lesion on her finger aredescribed.
PubMed was used to search the followingterms: bullous impetigo, pregnancy, and pyogenicgranuloma. All papers were reviewed; relevantarticles, along with their references, were evaluatedResults: A red ulcerated nodule with a collaretteof epithelium around the tumor and surroundingbullae appeared on the fifth digit of the left hand of a31-year-old woman who was at 36 weeks gestation. Abacterial culture grew methicillin sensitive S. aureus.An excisional biopsy was performed. Histologicfindings revealed not only a benign vascular tumorwith an infiltrate of mixed inflammatory cells, butalso an intraepidermal blister. She received oralantibiotics and there was complete resolution of thefinger lesion and infection with preservation of digitfunction.
Albeit uncommon, pyogenic granulomaand bullous impetigo may concurrently occur in thesame lesion. Therapeutic intervention should focuson treating both the benign skin tumor and theinfection.
大疱性脓疱疮是由金黄色葡萄球菌引起的一种浅表皮肤感染。化脓性肉芽肿是一种常见的良性肿瘤，常与先前的创伤有关。大疱性脓疱疮和化脓性肉芽肿可发生于孕妇。
描述一名孕妇手指病变同时存在化脓性肉芽肿和大疱性脓疱疮的特征。
使用PubMed搜索以下术语：大疱性脓疱疮、妊娠和化脓性肉芽肿。对所有论文进行了综述；对相关文章及其参考文献进行了评估。结果：一名妊娠36周的31岁女性左手第五指出现一个红色溃疡结节，肿瘤周围有上皮衣领样结构及周围大疱。细菌培养长出对甲氧西林敏感的金黄色葡萄球菌。进行了切除活检。组织学检查结果显示不仅有一个伴有混合性炎性细胞浸润的良性血管肿瘤，还有一个表皮内水疱。她接受了口服抗生素治疗，手指病变和感染完全消退，手指功能得以保留。
尽管罕见，但化脓性肉芽肿和大疱性脓疱疮可同时出现在同一病变中。治疗干预应侧重于治疗良性皮肤肿瘤和感染。
