te Beek Lowieke A M, van der Werf Marieke J, Richter Clemens, Borgdorff Martien W
KNCV Tuberculosis Foundation, The Hague, The Netherlands.
Emerg Infect Dis. 2006 Sep;12(9):1375-82. doi: 10.3201/eid1209.050553.
This study describes the epidemiology of extrapulmonary tuberculosis (TB) in the Netherlands from 1993 through 2001. We assessed whether the increasing numbers of inhabitants with a non-Western ethnic background had an effect on the number of extrapulmonary patients. We used data from the Netherlands Tuberculosis Register and included all cases of TB diagnosed in the Netherlands between January 1, 1993, and December 31, 2001. Information on age, sex, nationality, year of diagnosis, culture result, anatomic location of the site of disease, and HIV status was retrieved from the register. Of 13,258 patients with TB, 8216 (62%) had pulmonary TB, and 5042 (38%) had extrapulmonary TB. Non-Dutch nationals were more likely to have most types of extrapulmonary TB. The growth of the number of inhabitants with a non-Western ethnic background in the Netherlands explains the proportional growth of extrapulmonary TB. Physicians need to be aware of the changing clinical picture of TB.
本研究描述了1993年至2001年荷兰肺外结核病(TB)的流行病学情况。我们评估了非西方族裔背景居民数量的增加是否对肺外结核患者数量产生影响。我们使用了荷兰结核病登记处的数据,纳入了1993年1月1日至2001年12月31日期间在荷兰诊断出的所有结核病病例。从登记处获取了有关年龄、性别、国籍、诊断年份、培养结果、疾病部位的解剖位置以及艾滋病毒感染状况的信息。在13258例结核病患者中,8216例(62%)患有肺结核,5042例(38%)患有肺外结核。非荷兰籍国民更有可能患大多数类型的肺外结核。荷兰非西方族裔背景居民数量的增长解释了肺外结核的相应增长。医生需要意识到结核病临床表现的变化。