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2285根神经周围导管的炎症和感染并发症:一项前瞻性研究。

Inflammation and infection complications of 2285 perineural catheters: a prospective study.

作者信息

Neuburger M, Büttner J, Blumenthal S, Breitbarth J, Borgeat A

机构信息

Department of Anesthesiology, Berufsgenossenschaftliche Unfallklinik Murnau, Germany.

出版信息

Acta Anaesthesiol Scand. 2007 Jan;51(1):108-14. doi: 10.1111/j.1399-6576.2006.01173.x. Epub 2006 Nov 1.

Abstract

BACKGROUND

Perineural catheters (PNCs) are increasingly being used. Few data are available on the infectious complications of PNCs. The incidence and localization of local inflammation and infection associated with PNCs were assessed.

METHODS

PNCs placed under sterile conditions for regional anesthesia and post-operative analgesia were evaluated prospectively. Local inflammation was defined as redness, swelling or pain on pressure at the catheter insertion site. Infection was defined as purulent material at the catheter insertion site with or without the need for surgical intervention.

RESULTS

In total, 2285 PNCs were evaluated: 600 axillary, 303 interscalene, 92 infraclavicular, 65 psoas compartment, 574 femoral, 296 sciatic and 355 popliteal. Local inflammation occurred in 4.2% and infection in 3.2%. The duration of PNC placement was a risk factor (P < 0.05). Surgical intervention was necessary in 0.9%. No late complications occurred in any patient. Interscalene catheters were associated with an increased risk of infection (4.3%; P < 0.05). Anterior proximal sciatic catheters were associated with a lower risk of local inflammation (1.7%; P < 0.05) and infection (0.4%; P < 0.05). Staphylococcus epidermidis and Staphylococcus aureus were isolated in 42% and 58% of catheter tip cultures, respectively.

CONCLUSION

In the present study population, infection of PNCs was a rare occurrence, but the incidence increased with the duration of PNC placement, and close clinical monitoring is required.

摘要

背景

神经周围导管(PNCs)的使用越来越广泛。关于PNCs感染并发症的数据很少。评估了与PNCs相关的局部炎症和感染的发生率及部位。

方法

对在无菌条件下放置用于区域麻醉和术后镇痛的PNCs进行前瞻性评估。局部炎症定义为导管插入部位发红、肿胀或按压时疼痛。感染定义为导管插入部位有脓性物质,无论是否需要手术干预。

结果

共评估了2285根PNCs:600根腋部、303根肌间沟、92根锁骨下、65根腰大肌间隙、574根股部、296根坐骨和355根腘部。局部炎症发生率为4.2%,感染发生率为3.2%。PNC放置时间是一个危险因素(P<0.05)。需要手术干预的比例为0.9%。所有患者均未发生晚期并发症。肌间沟导管感染风险增加(4.3%;P<0.05)。坐骨神经前近端导管局部炎症(1.7%;P<0.05)和感染风险较低(0.4%;P<0.05)。分别在42%和58%的导管尖端培养物中分离出表皮葡萄球菌和金黄色葡萄球菌。

结论

在本研究人群中,PNCs感染很少见,但发生率随PNC放置时间增加,需要密切临床监测。

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