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在严重联合免疫缺陷小鼠体内的冷冻保存人卵巢组织异种移植中，长时间促性腺激素刺激后原始卵泡显著丢失。

Significant loss of primordial follicles after prolonged gonadotropin stimulation in xenografts of cryopreserved human ovarian tissue in severe combined immunodeficient mice.

作者信息

Maltaris Theodoros, Beckmann Matthias W, Mueller Andreas, Hoffmann Inge, Kohl Joachim, Dittrich Ralf

机构信息

Department of Obstetrics and Gynaecology, University Hospital Erlangen, Erlangen, Germany.

出版信息

Fertil Steril. 2007 Jan;87(1):195-7. doi: 10.1016/j.fertnstert.2006.05.058. Epub 2006 Oct 30.

DOI:10.1016/j.fertnstert.2006.05.058
PMID:17074335
Abstract

This study evaluated the effect of gonadotropin stimulation on the primordial follicle reserve of cryopreserved human ovarian tissue after transplantation in severe combined immunodeficient mice. We found that prolonged gonadotropin stimulation significantly reduces primordial follicles.

摘要

本研究评估了促性腺激素刺激对严重联合免疫缺陷小鼠移植后冷冻保存的人卵巢组织原始卵泡储备的影响。我们发现，延长促性腺激素刺激会显著减少原始卵泡。

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