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[猴中诱导性成血细胞增多症的宫内传播,与C型肿瘤病毒相关]

[Intrauterine transmission of induced hemoblastosis in monkeys, associated with type-C oncornavirus].

作者信息

Lapin B A, Indzhiia L V, Iakovleva L A, Bukaeva I A, Kokosha L V

出版信息

Vopr Onkol. 1975;21(8):54-63.

PMID:170744
Abstract

The possibility of intrauterine transmission of hemoblastosis was investigated in a group of 118 M. arctoides females with induced viral hemoblastosis. In the course of observations pregnancy occurred in 9 cases. Four of seven babies, delivered at term have developed hemoblastosis. The main signs of the disease were revealed in babies from the first days of their life. Hemoblastosis was accompanied with the appearance of a specific surface antigen and the presence of the "C" type oncornavirus in blood and organs of the babies, and also in cells of one embryo. Viral hemoblastosis was successfully passaged from one of the babies to three juvenile monkeys of the same species.

摘要

在一组118只诱发病毒性成血细胞增多症的熊猴雌性动物中,研究了成血细胞增多症宫内传播的可能性。在观察过程中,有9例怀孕。足月分娩的7个婴儿中有4个患上了成血细胞增多症。这些疾病的主要症状在婴儿出生后的头几天就显现出来了。成血细胞增多症伴随着特定表面抗原的出现,以及婴儿血液、器官以及一个胚胎细胞中存在“C”型肿瘤病毒。病毒性成血细胞增多症成功地从其中一个婴儿传播到了3只同物种的幼年猴子身上。

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