Olmez Akgün, Köse Gülşen, Turanli Güzide
Hacettepe University Faculty of Medicine, Department of Child Neurology, Ankara, Turkey.
Pediatr Neurol. 2006 Nov;35(5):348-51. doi: 10.1016/j.pediatrneurol.2006.06.014.
Cyclic vomiting syndrome is a disorder characterized by recurrent attacks of vomiting and intervals of normal health between vomiting episodes averaging 2-4 weeks. It has been described by a variety of names such as abdominal migraine, abdominal epilepsy, and periodic syndrome but now has been classified in the subgroup of childhood periodic syndromes that are commonly precursors of migraine. Topiramate is an antiepileptic drug used both in the treatment of epilepsy and in migraine prophylaxis. This report presents a child with cyclic vomiting syndrome with generalized epileptiform discharges who responded to topiramate therapy. The common features of epilepsy, migraine, and cyclic vomiting syndrome are discussed.
周期性呕吐综合征是一种以反复呕吐发作为特征的疾病，在呕吐发作期间有平均2至4周的正常健康间隔期。它曾有多种名称，如腹型偏头痛、腹型癫痫和周期性综合征，但现在已被归类为儿童周期性综合征亚组，这些综合征通常是偏头痛的先兆。托吡酯是一种抗癫痫药物，用于治疗癫痫和预防偏头痛。本报告介绍了一名患有周期性呕吐综合征且伴有全身性癫痫样放电的儿童，该患儿对托吡酯治疗有反应。文中讨论了癫痫、偏头痛和周期性呕吐综合征的共同特征。
