Hayes William J, VanGilder Deidra, Berendse Joseph, Lemon Michael D, Kappes John A
Department of Pharmacy Practice, South Dakota State University, Regional Health Medical Clinic, Rapid City, SD, USA.
South Dakota State University, College of Pharmacy and Allied Health Professions, Brown Clinic, Watertown, SD, USA.
Clin Exp Gastroenterol. 2018 Feb 26;11:77-84. doi: 10.2147/CEG.S136420. eCollection 2018.
Cyclic vomiting syndrome (CVS) is a disorder characterized by episodes of nausea and vomiting lasting for 1-5 days followed by asymptomatic periods. The etiology of CVS is unknown, but it shares similar characteristics to migraine headaches. CVS is generally classified as having four phases: prodromal, acute/vomiting/hyperemesis, recovery, and remission/interepisodic. Current management strategies include trigger avoidance, abortive and prophylactic medication therapies, and supportive care. The goal of therapy for the remission phase is prophylaxis of further episodes. Antidepressant, antiepileptic, and antimigraine medications show an overall reduction or remission of CVS symptoms in more than 70% of patients. This article provides a summary of diagnostic strategies and reviews current management strategies for CVS.
周期性呕吐综合征（CVS）是一种以恶心和呕吐发作为特征的疾病，发作持续1 - 5天，随后为无症状期。CVS的病因尚不清楚，但它与偏头痛有相似的特征。CVS通常分为四个阶段：前驱期、急性/呕吐/剧吐期、恢复期和缓解期/发作间期。目前的治疗策略包括避免触发因素、使用终止发作和预防性药物治疗以及支持性护理。缓解期治疗的目标是预防进一步发作。抗抑郁药、抗癫痫药和抗偏头痛药物在超过70%的患者中可使CVS症状总体减轻或缓解。本文总结了诊断策略并综述了CVS的当前治疗策略。
