Trabelsi Alouane Leila, Bedioui Abdelmoncef, Rahal Khaled
Ecole Supérieure des Sciences et Techniques de la Santé de Tunis, Université El Mannar, Département de nutrition, BP 176, Bab Suika, 1006 Tunis, Tunisie.
Bull Cancer. 2006 Oct;93(10):1055-61.
Malnutrition increases the risks of morbidity and mortality in cancer patients. It is characterized by changes in cellular membrane integrity and alterations in fluid balance, both of which can be detected by bioelectrical impedance analysis (BIA). We investigated whether BIA-mesured variables could detect malnutrition, as defined by body mass index (BMI) and anthropometric indices, in 83 Tunisian cancer patients (18 men and 65 women) hospitalized in surgery. The investigations occurred within the first 24 hours following hospital admission. Analysis revealed that 4.8 % of the patients were at risk for malnutrition according to body mass index. By impedancemetry, 26.5 % of all patients had free-fat mass index (FFMI) below the normal range and 15.6 % had a low fat mass index (FMI) despite a normal or relatively high BMI. While males lose their fatty reserves early, females tend to lose free-fat, muscular mass regardless of their BMI. The BMI can be misleading in an overweight or obese patient and conceal losses in muscular mass in patients exposed to latent malnutrition. The FFMI and FMI appear to be better indicators of the nutritional status than the BMI.
营养不良会增加癌症患者发病和死亡的风险。其特征是细胞膜完整性改变和体液平衡失调，这两者均可通过生物电阻抗分析（BIA）检测出来。我们调查了在83名因手术住院的突尼斯癌症患者（18名男性和65名女性）中，BIA测量的变量是否能检测出由体重指数（BMI）和人体测量指标所定义的营养不良。调查在患者入院后的头24小时内进行。分析显示，根据体重指数，4.8%的患者存在营养不良风险。通过阻抗测量法，尽管BMI正常或相对较高，但所有患者中有26.5%的人自由脂肪质量指数（FFMI）低于正常范围，15.6%的人脂肪质量指数（FMI）较低。男性较早失去脂肪储备，而女性无论BMI如何，往往会失去自由脂肪和肌肉质量。在超重或肥胖患者中，BMI可能会产生误导，并掩盖潜在营养不良患者的肌肉质量损失。FFMI和FMI似乎比BMI更能准确反映营养状况。
