Daghfous Hafaoua, El Ayeb Wejdène, Alouane Leila, Tritar Fatma
Tunis Med. 2014 Dec;92(12):737-42.
Malnutrition and cachexia were a frequent problem in lung cancer and increases the risks of morbidity and mortality in these patients. Bioelectrical impedance analysis (BIA) is easy, non-invasive and reproducible method that can be performed.
Evaluate nutritional status in patients with primary lung cancer by Mini Nutritional Assessment (MNA), BIA and anthropometric values (weight, arm and calf circumferences) and correlate the nutritional parameters to severity of cancer and histopathology.
The nutritional status of 73 cases of primary lung cancer was evaluated by anthropometric parameters, MNA test and impedencemetrie Results: According to body mass index (BMI), malnutrition, overweight and obesity were noted in 34,2%, 13,7% and 5,5%. According to BMI, free-fat mass index (FFMI) and fat mass index (FMI), the investigations occurred malnutrition and depletion of muscle in respectively 19,2% and 23,3% of cases. Fat depletion was noted in 21,9%. Overweight and obesity were detected in 6,8% and 5,5% of cases. Assessment by MNA, revealed that 28,7% of patients were already malnourished and 49,3% of patients were at risk of malnutrition. A significant correlation existed between the score of MNA and arm and calf circumferences, FFMI and FMI. FMI was significantly lower in group of patients with small lung carcinoma.
Only FFMI allows early detection of malnutrition in cancer patients overestimated by measuring BMI and arm circumference was the better indicator of depletion of muscle.
营养不良和恶病质在肺癌患者中是常见问题，会增加这些患者发病和死亡的风险。生物电阻抗分析（BIA）是一种简便、无创且可重复进行的方法。
通过微型营养评定法（MNA）、生物电阻抗分析和人体测量值（体重、上臂和小腿围）评估原发性肺癌患者的营养状况，并将营养参数与癌症严重程度和组织病理学相关联。
通过人体测量参数、MNA测试和阻抗测量评估73例原发性肺癌患者的营养状况。结果：根据体重指数（BMI），34.2%、13.7%和5.5%的患者存在营养不良、超重和肥胖。根据BMI、去脂体重指数（FFMI）和体脂指数（FMI），分别有19.2%和23.3%的病例存在营养不良和肌肉消耗。21.9%的病例存在脂肪消耗。6.8%和5.5%的病例检测到超重和肥胖。通过MNA评估发现，28.7%的患者已经营养不良，49.3%的患者有营养不良风险。MNA评分与上臂和小腿围、FFMI和FMI之间存在显著相关性。小肺癌患者组的FMI显著较低。
只有FFMI能够早期发现癌症患者中被BMI高估的营养不良情况，而上臂围是肌肉消耗的更好指标。
