Abudu A, Carter S R, Grimer R J
Royal Orthopaedic Hospital Oncology Service, Birmingham, England.
J Bone Joint Surg Br. 1996 Jul;78(4):652-7.
Improvement in the life expectancy of patients with primary bone tumours has led to increased emphasis on limb salvage and preservation of function. Between 1979 and 1994 we used custom-made endoprostheses in 18 patients to reconstruct diaphyseal defects after excision of primary bone tumours. The mean age at operation was 26 years (9 to 64) and the median follow-up 65 months (6 to 188). Fifteen patients have survived and are free from local or metastatic disease. Local recurrence developed in one patient. Using the modified Enneking functional scoring system, 77% of the patients achieved 80% or more of their premorbid functional capability. Mechanical loosening, limb shortening and secondary osteoarthritis were the main complications. There were no infections. We conclude that diaphyseal endoprostheses offer a good clinical and functional outcome in the lower limb.
原发性骨肿瘤患者预期寿命的提高,使得人们越来越重视肢体挽救和功能保留。1979年至1994年间,我们使用定制的内置假体为18例患者重建原发性骨肿瘤切除术后的骨干缺损。手术时的平均年龄为26岁(9至64岁),中位随访时间为65个月(6至188个月)。15例患者存活,无局部或转移性疾病。1例患者出现局部复发。采用改良的Enneking功能评分系统,77%的患者达到了病前功能能力的80%或更高。机械性松动、肢体短缩和继发性骨关节炎是主要并发症。无感染发生。我们得出结论,骨干内置假体在下肢可提供良好的临床和功能结果。