内淋巴囊直流电电位对窒息的反应。

Response of the endolymphatic sac d.c. potential to asphyxia.

作者信息

Mori N, Uozumi N, Sakai S

机构信息

Department of Otolaryngology, Kagawa Medical School, Japan.

出版信息

Acta Otolaryngol. 1991;111(1):70-4. doi: 10.3109/00016489109137356.

DOI:10.3109/00016489109137356

PMID:1707577

Abstract

The effect of asphyxia on the endolymphatic sac d.c. potential (ESP) was examined in the guinea pig. Asphyxia was caused for 1.5 min by stopping the respirator. The ESP decreased in amplitude during asphyxia. After the termination of asphyxia the ESP showed a diphasic recovery pattern. When respiration was resumed, the ESP decreased again following a transient recovery. Thereafter, the ESP showed a gradual recovery. beta-blocker (propranolol) inhibited a temporary decrease in the ESP after the resumption of respiration, but not alpha-blocker (phentolamine). The result indicates that the ESP decrease after the resumption of respiration is induced by beta-adrenergic action.

摘要

在豚鼠身上研究了窒息对内淋巴囊直流电位（ESP）的影响。通过停止呼吸机造成1.5分钟的窒息。窒息期间ESP的幅度下降。窒息终止后，ESP呈现双相恢复模式。恢复呼吸时，ESP在短暂恢复后再次下降。此后，ESP逐渐恢复。β受体阻滞剂（普萘洛尔）抑制了恢复呼吸后ESP的暂时下降，但α受体阻滞剂（酚妥拉明）则没有。结果表明，恢复呼吸后ESP的下降是由β-肾上腺素能作用引起的。