Hoste Eric A J, Kellum John A
Intensive Care Unit, Ghent University Hospital, Ghent, Belgium.
Curr Opin Crit Care. 2006 Dec;12(6):531-7. doi: 10.1097/MCC.0b013e3280102af7.
To review recent advances in the definitions and diagnostic criteria for acute renal failure and acute kidney injury. To explore how these changes impact the epidemiology and clinical implications for patients in the intensive care unit.
Recently published consensus criteria for the definition of acute renal failure/acute kidney injury have led to significant changes in how we think about this disorder. Studies from around the world, both in and out of the intensive care unit, have shown a dramatic incidence of acute kidney injury and high associated mortality. This review considers these new findings and their historical context, and attempts to shed new light on this old problem.
Small changes in kidney function in hospitalized patients are important and impact on outcome. RIFLE criteria provide a uniform definition of acute kidney injury and are increasingly used in literature.
回顾急性肾衰竭和急性肾损伤定义及诊断标准的最新进展。探讨这些变化如何影响重症监护病房患者的流行病学及临床意义。
最近发表的急性肾衰竭/急性肾损伤定义的共识标准，已使我们对该疾病的认识发生了重大改变。来自世界各地重症监护病房内外的研究表明，急性肾损伤的发病率很高，且相关死亡率也很高。本综述考虑了这些新发现及其历史背景，并试图为这一老问题提供新的见解。
住院患者肾功能的微小变化很重要，且会影响预后。RIFLE标准为急性肾损伤提供了统一的定义，并且在文献中越来越多地被使用。
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