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[中间丝在唾液腺及唾液腺肿瘤中的分布]

[Distribution of intermediate filaments in the salivary glands and salivary gland tumors].

作者信息

Situ Z Q

机构信息

College of Stomatology, Fourth Military Medical University, Xi'an.

出版信息

Zhonghua Kou Qiang Yi Xue Za Zhi. 1990 Sep;25(5):262-4, 317.

PMID:1707776
Abstract

13 cases of salivary glands and 30 of salivary gland tumors were studied by ABC method with 6 monoclonal antibodies to intermediate filaments and one to microfilament. The results showed that the distribution of intermediate filaments in salivary glands had their regularity. According to the reaction to the antibodies, these tumors could be divided into 3 groups and 3 subgroups. The findings also suggested that in the salivary gland tissue the epithelial cells which mainly contained the 54 Kd keratin and the epithelial cells which mainly contained 57/66 Kd keratin were the origin of the salivary gland tumors. The actin-positive myoepithelial cells might play a role in some tumor formation.

摘要

用6种抗中间丝单克隆抗体和1种抗微丝单克隆抗体,采用ABC法对13例涎腺及30例涎腺肿瘤进行了研究。结果显示,中间丝在涎腺中的分布有其规律性。根据对抗体的反应,这些肿瘤可分为3组和3个亚组。研究结果还提示,在涎腺组织中,主要含54Kd角蛋白的上皮细胞和主要含57/66Kd角蛋白的上皮细胞是涎腺肿瘤的起源。肌动蛋白阳性的肌上皮细胞可能在某些肿瘤形成中起作用。

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