Hewell Kristen, Hoste Renee Rienecke, le Grange Daniel
Department of Psychiatry, The University of Chicago, 5841 South Maryland Avenue, MC 3077, Chicago, IL 60637, USA.
Int J Eat Disord. 2006 Nov;39(7):594-7. doi: 10.1002/eat.20290.
This objective of this study was to investigate the recruitment rate for a clinical treatment trial for adolescents with bulimia nervosa.
Recruitment rates for a 5-year randomized controlled trial for adolescent bulimia nervosa were analyzed.
Although the rate of randomization fluctuated over the course of the study, the overall rate of participants recruited was fairly consistent. The number of participants who were assessed for the study but who did not qualify, and the number of participants who qualified for the study but who chose not to join, were also consistent.
These findings suggest that it is feasible to recruit adolescents for a bulimia nervosa treatment trial. A better understanding of the reasons behind a participant's decision to stay in a treatment study versus discontinue a treatment study, as well as differences between adult and adolescent patients, could aid in the design of future treatment studies.
本研究的目的是调查神经性贪食症青少年临床治疗试验的招募率。
分析了一项针对青少年神经性贪食症的为期5年的随机对照试验的招募率。
尽管随机化率在研究过程中有所波动，但招募的参与者总体率相当一致。接受研究评估但不符合条件的参与者数量，以及符合研究条件但选择不加入的参与者数量也保持一致。
这些发现表明，招募青少年进行神经性贪食症治疗试验是可行的。更好地理解参与者决定继续或停止治疗研究背后的原因，以及成人和青少年患者之间的差异，可能有助于未来治疗研究的设计。
