Leigh David A, Thomson Andrew R
University of Edinburgh, School of Chemistry, The King's Buildings, West Mains Road, Edinburgh EH9 3JJ, UK.
Org Lett. 2006 Nov 9;8(23):5377-9. doi: 10.1021/ol062284j.
[Structure: see text] Protonation controls the location of a dual binding mode macrocycle in a [2]rotaxane. In the neutral form, amide-amide hydrogen bonds hold the macrocycle over a dipeptide residue; when the thread is protonated, polyether-ammonium cation interactions dominate and the macrocycle changes position.
[结构：见正文] 质子化控制着双结合模式大环在[2]轮烷中的位置。在中性形式下，酰胺-酰胺氢键将大环固定在二肽残基上方；当链被质子化时，聚醚-铵阳离子相互作用起主导作用，大环改变位置。
