Rocco Bernardo, Gregori Andrea, Stener Silvio, Santoro Luigi, Bozzola Andrea, Galli Stefano, Knez Roberto, Scieri Francesco, Scaburri Alessandra, Gaboardi Franco
Division of Urology, European Institute of Oncology, Milan, Italy.
Eur Urol. 2007 Apr;51(4):996-1003. doi: 10.1016/j.eururo.2006.10.014. Epub 2006 Oct 23.
Urinary incontinence is one of the major drawbacks of radical retropubic prostatectomy (RRP). One of the possible reasons for this urinary incontinence is a postoperative deficiency of the rhabdosphincter (RS). It has been recently demonstrated that reconstruction of the posterior aspects of the RS allows a rapid recovery of continence after RRP. This study evaluated the application of this technique in videolaparoscopic radical prostatectomy (VLRP), assessing the percentage of continent patients at 3, 30, and 90 d after catheter removal.
A two-arm prospective comparative trial was carried out with 31 patients recruited for each arm. Group A underwent standard VLRP and group B underwent VLRP with RS reconstruction (VLRP-R). Continence was defined as no pads or one diaper/24h and was assessed 3, 30, and 90 d after the procedure.
At catheter removal, 74.2% versus 25% (p=0.0004) of patients were continent with the VLRP-R technique versus VLRP, respectively. A statistically significant difference was present at 30 d (83.8% vs. 32.3%; p=0.0001) At 90 d the difference, although still present, was not statistically significant (92.3% vs. 76.9%; p=0.25).
In this preliminary report, the posterior reconstruction of the RS appears to be an easy and feasible technique even in a laparoscopic setting. Time to continence recovery was significantly shortened.
尿失禁是耻骨后根治性前列腺切除术(RRP)的主要缺点之一。导致这种尿失禁的一个可能原因是术后横纹括约肌(RS)功能不足。最近有研究表明,RS后位重建可使RRP术后控尿功能迅速恢复。本研究评估了该技术在视频腹腔镜根治性前列腺切除术(VLRP)中的应用,评估了拔除导尿管后3天、30天和90天控尿患者的比例。
进行双臂前瞻性对照试验,每组招募31例患者。A组接受标准VLRP,B组接受RS重建的VLRP(VLRP-R)。控尿定义为无需使用尿垫或24小时使用一片尿布,并在术后3天、30天和90天进行评估。
拔除导尿管时,VLRP-R技术组与VLRP组的控尿患者比例分别为74.2%和25%(p=0.0004)。30天时存在统计学显著差异(83.8%对32.3%;p=0.0001)。90天时差异仍然存在,但无统计学意义(92.3%对76.9%;p=0.25)。
在本初步报告中,即使在腹腔镜手术中,RS后位重建似乎也是一种简单可行的技术。控尿恢复时间显著缩短。